000			04916cam a2200481Ii 4500
988			_aSpringer_Medicine_2017
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003			ES-MaUEC
005			20230102112617.0
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007			cr cnu|||unuuu
008			160831t20162017ja a ob 001 0 eng d
020			_a4431560394 _q(electronic bk.)
020			_a9784431560395 _q(electronic bk.)
020			_z4431560378
020			_z9784431560371 _q(print)
035			_a(OCoLC)957557877 _z(OCoLC)957617615 _z(OCoLC)957739376
040			_aN$T _cN$T _dGW5XE _dIDEBK _dYDX _dEBLCP _dN$T _dCASUM _dOCLCO _dOCLCA _dMERER _dOCLCO _dUAB _dOCLCO _dIOG _dESU _dZ5A _dOCLCO _dJBG _dIAD _dICW _dICN _dOTZ _dOCLCQ _dOCLCO _dU3W _dOCLCO _dOCLCA _dES-MaUEC _bspa
050		4	_aRJ406.M83 _b2017 EB
245	0	0	_aKawasaki disease : _bcurrent understanding of the mechanism and evidence-based treatment _cBen Tsutomu Saji, Jane W. Newburger, Jane C. Burns, Masato Takahashi, editors.
264		1	_aJapan _bSpringer _c[2016].
264		4	_c2017
300			_a1 recurso en línea (xix, 552 páginas) _bilustraciones (algunas a color)
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
500			_aSpringerLink
504			_aIncluye referencias bibliográficas e índice
505	0		_aForeword; Preface; References; Contents; Part I: Basic Research; The History of Kawasaki Disease: A Personal Perspective; Introduction; The Era of Clinical Description and Pathologic Recognition: 1960-1984; Back to the Future: 1871-1984 and Other Riddles of KD; The Era of Enhanced Discovery and International Collaboration: 1984-2015; References; Histopathology of Coronary Arteritis in Acute Kawasaki Disease and Murine Systemic Vasculitis Induced by Candida Albicans Cell...; Introduction; Histopathological Characteristics of Coronary Arteritis in Acute KD
505	8		_aAdvances in TreatmentAdvances in Genetics; Advances in Biomarkers and Diagnostic Tests; Advances in Understanding Long-Term Outcomes; References; Part II: Epidemiology; Epidemiologic Perspectives; Historical Perspective; KD Surveillance: Moving Forward; KD Surveillance: Prescription for the Future; References; Update on Nationwide Surveys and Epidemiologic Characteristics of Kawasaki Disease in Japan; Introduction; Methods of the Nationwide Surveys; Results of Nationwide Surveys; What We Have Learned from the Descriptive Epidemiology; Conclusions; References
505	8		_aIdentification of Novel Kawasaki Disease Susceptibility Genes by Genome-Wide Association StudiesIntroduction; History of the Genetic Study of KD; Genomic Studies of KD in the Post-Genomic era; ITPKC; CASP3; FCGR2A; BLK; CD40; HLA class II; Current Understandings and Recognition; Recent Advances; References; Immunological Abnormalities and Use of Biomarkers and Cytokines to Predict the Severity of Kawasaki Disease; Introduction; KD and Hypercytokinemia; Which Cytokines/Biomarkers Best Predict KD Severity?; Conclusions; References; Pathophysiology of Kawasaki Disease; Introduction; History
505	8		_aThe C. Albicans Cell Wall Polysaccharide-Induced Murine Vasculitis ModelModel Development and Description of the Vasculitis-Inducing Agent; Histopathological Characteristics of C. Albicans Polysaccharide-Induced Murine Vasculitis; Relationship of Mouse Genetic Background to Cytokines and Vasculitis; Response of C. Albicans Polysaccharide-Induced Vasculitis to Treatment; References; Histopathological Characteristics of Noncardiac Organs in Kawasaki Disease; Introduction; Brief Overview of Systemic Vascular Lesions in KD; Histological Changes in Noncardiac Organs in KD; References
505	8		_aThe Three Linked Pathological Processes of KD VasculopathyRecent Advances in Etiological, Genomic, and Gene Expression Studies; Conclusions; References; Update on Pathogenesis: Lessons Learned from Animal Models of Disease; Introduction; T-Cell Activation and Survival and the Role of Costimulation; Murine Models of KD; References; The Climate-KD Link; References; Kawasaki Disease Shock Syndrome; Introduction; Incidence and Demographics; Mechanisms; Clinical Course and Treatment; Differential Diagnosis; Future Perspectives; References; Future Directions in Kawasaki Disease Research
588	0		_aOnline resource; title from PDF title page (SpringerLink, viewed September 1, 2016).
650		7	_aSistema linfático _xEnfermedades _2embne _9215480
700	1		_aBurns, Jane C. _eeditor literario
700	1		_aNewburger, Jane W., _eeditor literario
700	1		_aSaji, Ben Tsutomu, _eeditor literario
700	1		_aTakahashi, Masato, _d1933- _eeditor literario
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=http://link.springer.com/10.1007/978-4-431-56039-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2018 _dz _e- _zSI