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| 001 | 88289 | ||
| 003 | ES-MaUEC | ||
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| 008 | 161109s2016 ne | s |||| 0|eng d | ||
| 020 | _a9789402409451 | ||
| 024 | 7 |
_a10.1007/978-94-024-0945-1 _2doi |
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| 040 | _aES-MaUEC | ||
| 050 | 4 |
_aQP801.R47 _bT44 2016 EB |
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| 245 | 0 | 4 |
_aThe Biochemistry of retinoid signaling II : _bthe physiology of Vitamin A - uptake, transport, metabolism and signaling _cedited by Mary Ann Asson-Batres, Cecile Rochette-Egly |
| 260 |
_aDordrecht _bSpringer _c2016 |
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| 300 |
_a1 recurso en línea (IX, 263 p.) _b52 ilustraciones, 40 ilustraciones en color |
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| 336 |
_aTexto (visual) _btxt _2rdacontent |
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| 337 |
_aelectrónico _bc _2rdamedia |
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| 338 |
_arecurso electrónico _bcr _2rdacarrier |
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| 490 | 1 |
_aSubcellular Biochemistry _x0306-0225 _v81 |
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| 505 | 0 | _aPreface, Mary Ann Asson-Batres and Cecile Rochette-Egly -- In Memorium -- 1 Carotenoids and Retinoids: Nomenclature, Chemistry, and Analysis, Earl H. Harrison and Robert W. Curley, Jr -- 2 Functions of Intracellular Retinoid Binding-Proteins, Joseph L. Napoli -- 3 Vitamin A Transport and Cell Signaling by the Retinol-Binding Protein Receptor STRA6, Noa Noy -- 4 Vitamin A Absorption, Storage and Mobilization, William S. Blaner, Yang Li, Jason J. Yuen, Seung-Ah Lee, and Robin D. Clugston -- 5 Retinoic Acid Synthesis and Degradation, Natalia Y. Kedishvili -- 6 Cellular Retinoic Acid Binding Proteins: Genomic and Non-Genomic Functions and their Regulation, Li-Na Wei -- 7 Non-Classical Transcriptional Activity of Retinoic Acid, Noa Noy -- 8 Vitamin A as PKC Co-factor and Regulator of Mitochondrial Energetics, Ulrich Hammerling -- 9 Vitamin A and Vision, John C Saari -- Index | |
| 520 | _aThe role of vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes, and the essential details of its mechanism of action have been revealed by investigations carried out by researchers using vertebrate and more recently invertebrate models to study a multiplicity of processes and conditions, encompassing embryogenesis, postnatal development to old age. A wealth of intercellular interactions, intracellular signaling systems, and molecular mechanisms have been described and the overall conclusion is that retinoic acid is essential for life. This book series, with chapters authored by experts in every aspect of this complex field, unifies the knowledge base and mechanisms currently known in detailed, engaging, well-illustrated, focused chapters that synthesize information for each specific area. In view of the recent information explosion in this field, it is timely to publish a contemporary, comprehensive, book series recapitulating the most exciting developments in the field and covering fundamental research in molecular mechanisms of vitamin A action, its role in physiology, development, and continued well-being, and the potential of vitamin A derivatives and synthetic mimetics to serve as therapeutic treatments for cancers and other debilitating human diseases. Volume II is divided into nine chapters contributed by prominent experts in their respective fields. Each chapter starts with the history of the area of research. Then, the key findings that contributed to development of the field are described, followed by a detailed look at key findings and progress that are being made in current, ongoing research. Each chapter is concluded with a discussion of the relevance of the research and a perspective on missing pieces and lingering gaps that the author recommends will be important in defining future directions in vitamin A research | ||
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_aVitamina A _9153314 _0comprobar BNE19974207362 _2embne |
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_9668476 _aQuímica bioorgánica _0LocalZ |
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_aAsson-Batres, Mary Ann _eeditor literario _0Local _986377 |
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_aRochette-Egly, Cecile _eeditor literario _9101939 _0Local |
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_aSubcellular Biochemistry _x0306-0225 _v81 _0http://id.loc.gov/authorities/names/no97030144 _9133378 |
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| 856 | 4 | 0 | _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-024-0945-1zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
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