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| 008 | 161210s2016 gw | s |||| 0|eng d | ||
| 020 | _a9783319484181 | ||
| 024 | 7 |
_a10.1007/978-3-319-48418-1 _2doi |
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| 040 | _aES-MaUEC | ||
| 050 | 4 |
_aR1 _b.A337 2016 EB |
|
| 100 | 1 |
_aAgarwal, Ashok _0http://id.loc.gov/authorities/names/nb2011002412 _0Local _985093 |
|
| 245 | 1 | 0 |
_aProteomics in Human Reproduction : _bBiomarkers for Millennials _cby Ashok Agarwal, Luna Samanta, Ricardo P. Bertolla, Damayanthi Durairajanayagam, Paula Intasqui. |
| 260 |
_aCham, Switzerland _bSpringer _c2016 |
||
| 300 |
_a1 recurso en línea (XV, 124 p.) _b9 ilustraciones |
||
| 336 |
_aTexto (visual) _btxt _2rdacontent |
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| 337 |
_aelectrónico _bc _2rdamedia |
||
| 338 |
_arecurso electrónico _bcr _2rdacarrier |
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| 490 | 1 |
_aSpringerBriefs in Reproductive Biology _x2194-4253 |
|
| 505 | 0 | _aIntroduction -- Proteomics -- Proteomics and Male Infertility -- Role of Proteomics in Female Infertility -- Proteomics in Assisted Reproduction -- Challenges of Proteomic Studies in Human Reproduction -- What Does the Future Hold? -- Conclusions. | |
| 520 | _aThis Brief explores the use of proteomics as a tool for biomarker discovery in human reproduction and summarizes current findings and trends of proteomic studies in both male and female infertility. This simplifies this important but complex topic and equips the novice reader with sufficient background information on the use of proteomics in human reproduction. The up-to-date scenario on proteomic investigations will also appeal to researchers and post graduate students looking to keep abreast with the latest developments in reproductive research. This review summarizes current findings of contemporary proteomic studies on infertility in both males and females with various reproductive pathologies, and its use in predicting the outcome of assisted reproduction. In human reproduction, the search for biomarkers via proteomics is a fast-evolving approach that involves the analysis of proteins in the reproductive tissues and fluids, such as the male gametes, seminal plasma, ovarian and endometrial tissue, and follicular and uterine fluid. By comparing the protein profile of a healthy, fertile individual against that of an infertile individual, the differentially expressed proteins may give an indication to certain proteins that could serve as useful biomarkers that are related to infertility. As proteomic studies continue to unravel the dynamic proteome behind various infertility conditions, there is potential for the discovery of prognostic markers that could ultimately help in both natural and assisted human reproduction. | ||
| 650 | 0 | 7 |
_aSalud reproductiva _2embne _9162207 |
| 650 | 0 | 7 |
_9430647 _aProteómica _2embne |
| 700 | 1 |
_aSamanta, Luna. _9101821 _0Local |
|
| 700 | 1 |
_aBertolla, Ricardo P. _9101822 _0Local |
|
| 700 | 1 |
_aDurairajanayagam, Damayanthi _0Local _986862 |
|
| 700 | 1 |
_aIntasqui, Paula _0Local _9101823 |
|
| 830 | 0 |
_aSpringerBriefs in Reproductive Biology _x2194-4253 _0http://id.loc.gov/authorities/names/no2014005812 _9133198 |
|
| 856 | 4 | 0 | _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-48418-1zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
| 907 |
_a.b12982453 _b10-10-17 _c08-03-17 |
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