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008 161107s2016 gw | s |||| 0|eng d
020 _a9783319460918
024 7 _a10.1007/978-3-319-46091-8
_2doi
040 _aES-MaUEC
050 4 _aRC271.P76
_bR475 2016 EB
245 1 0 _aResistance to Tyrosine Kinase Inhibitors
_cedited by Daniele Focosi.
260 _aCham, Switzerland
_bSpringer
_c2016
300 _a1 recurso en línea (XIII, 188 p.)
_b8 ilustraciones, 6 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aResistance to Targeted Anti-Cancer Therapeutics
_x2196-5501
505 0 _aTyrosine Kinase Signaling Pathways in Normal and Cancer Cells -- Resistance to Tyrosine Kinase Inhibitors in different types of solid cancer -- The Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: An Overview -- Resistance to FLT3 Inhibitors -- Resistance to ALK inhibitors -- Resistance to Angiokinase Inhibitors -- Indications for Tyrosine Kinase Inhibitors in the Treatment of Solid Tumors.
520 _aThe volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors.
650 7 _aResistencia a los medicamentos
_2embne
_9146972
650 7 _aCáncer
_xInvestigación
_2embne
_9182523
700 1 _aFocosi, Daniele
_eeditor literario
_0Local
_9101702
830 0 _aResistance to Targeted Anti-Cancer Therapeutics
_x2196-5501
_0http://id.loc.gov/authorities/names/n2013186812
_9133185
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-46091-8zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12981886
_b10-10-17
_c08-03-17
942 _2lcc
_cLE
945 _aRC271.P76 R475 2016 EB
_g1
_ieBOOK
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988 _aEBOOK, EBSPRINGER
998 _am
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