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020 _a9783319458656
024 7 _a10.1007/978-3-319-45865-6
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRB170
_b2016 EB
245 0 0 _aBiochemistry of Oxidative Stress :
_bPhysiopathology and Clinical Aspects
_cedited by Ricardo Jorge Gelpi, Alberto Boveris, Juan José Poderoso
264 1 _aCham
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (XI, 454 páginas)
_b74 ilustraciones, 47 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aAdvances in Biochemistry in Health and Disease
_v16
505 0 _aIntroduction -- Section 1 GENERAL ASPECTS: 1 The concept of oxidative stress after 30 years -- 2 Evolution of atmospheric oxygen and oxygen metabolism -- 3 Mitochondria as origin of cellular oxidative stress -- 4 Biochemistry and physiology of mtNOS -- 5 Biochemistry of nitrogen reactive species -- 6 Biochemistry of nitro fatty acids -- 7 Mammalian adaptation to life at high altitude -- 8 Metabolic syndrome and oxidative stress in rat pancreas -- 9 Progesterone prevents mitochondrial dysfunction and oxidative stress in the spinal cord of wobbler mice -- 10 Mitochondrial transfer by intercellular nanotubes -- Section 2 CARDIOVASCULAR: 11 Role of Oxidative Stress in Subcellular Defects in Ischemic Heart Disease -- 12 Regulation of protein nitrosylation by Trx1 -- 13 Inhibition of adenylyl cyclase type 5 increases longevity and healthful aging through oxidative stress protection -- 14 Antioxidant supplementation in elderly cardiovascular patients -- 15 Rupture of redox homeostasis in a model of pulmonary artery -- 16 Mitochondrial reactive oxygen species triggered by the cardiac renin-angiotensin-aldosterone system -- 17 Mitochondrial complex I inactivation and increased autooxidation after ischemia-reperfusion in the stunned heart -- 18 Oxidized LDL and atherogenesis -- 19 Reactive oxygen species and cyclooxygenase products in the regulation of blood flow in small vessels -- 20 Thioredoxin-1 attenuates postischemic ventricular and mitochondrial dysfunctions -- 21 Nitro-arachidonic acid reduces the damaged area in rat myocardial infarction -- 22 Inhaled particulate matter and myocardial dysfunction -- Section 3 NEURODEGENERATION AND NEURONAL FUNCTION: 23 Effect of lipoic acid in the triple transgenic mouse model of Alzhaimer's disease -- 24 Neurovascular coupling mediated by NO in the hippocampus -- 25 Protection from neurodegeneration: signaling and mitocondrial regulation -- 26 Oxidative stress and neurodegeneration -- 27 Oxidative stress, metabolic syndrome and Alzheimerś disease -- 28 Systemic oxidative stress in patients with neurodegenerative diseases -- Section 4 CANCER: 29 Oxygen metabolism and oxidative stress in cancer cells -- 30 Mitochondrial biogenesis is required for survival and propagation of cancer cells -- 31 Tumor immunology & immunotherapy in patients -- 32 Oncogene-induced Nrf2 repression as adaptive response of cancer cells to acquire a pro-oxidant state favoring cell survival and in vivo tumor growth -- 33 Mitochondrial dynamics regulate oxidative metabolism in Leydig tumor cells -- Index
520 _aThe strongest point of this book titled zBiochemistry of Oxidative Stress: Physiopathology and Clinical Aspectsy, is that the academic and scientific background of the authors/editors guarantee the authorship of a book comprising all aspects of oxidative stress, ranging from very molecular aspects, to clinical application, including the antioxidant therapy. Of particular importance is the fact that the aforementioned aspects are described in the book in a general section and in three different and important pathologies, such as cardiovascular diseases, neurodegenerative diseases, and cancer. The importance of these pathologies lays in the fact that, taken separately or together, they represent by far the leading cause of death in the world. Finally, all the chapters have been written by highly recognized authorities in the field of their investigations. At least to our knowledge, this is the first book with this characteristics in the field of oxidative stress
988 _aEBOOK, EBSPRINGER
650 0 7 _aEstrés oxidativo
_2embne
_9158905
650 0 7 _aFisiología celular
_2embne
_9165668
700 1 _aGelpi, Ricardo Jorge
_eeditor literario
_0Local
_9101699
700 1 _aBoveris, Alberto
_eeditor literario
_0Local
_9101700
700 1 _aPoderoso, Juan José.
_eeditor literario
_9101701
_0Local
830 0 _aAdvances in Biochemistry in Health and Disease
_v16
_9133167
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-45865-6zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783319458656
907 _a.b12981862
_b10-10-17
_c08-03-17
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998 _b06/2020
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