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001			88122
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008			161214s2016 gw | s |||| 0|eng d
020			_a9783319414485
024	7		_a10.1007/978-3-319-41448-5 _2doi
040			_aES-MaUEC
050		4	_aQP551 _b.M634 2016 EB
245	0	0	_aModern Proteomics ; Sample Preparation, Analysis and Practical Applications _cedited by Hamid Mirzaei, Martin Carrasco
260			_aCham, Switzerland _bSpringer _c2016
300			_a1 recurso en línea (IX, 533 p.) _b180 ilustraciones, 130 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v919
505	0		_aSample Origin -- Sample Preparation for Proteomic Analyses by Mass Spectrometry -- Plant structure and specificity - challenges and sample preparation considerations for proteomics -- Protein Fractionation and Enrichment for Proteomics -- High Performance Liquid Chromatography -- Mass Analyzers -- Top-Down Mass Spectrometry: Proteomics to Proteoforms -- Platforms and pipelines for Proteomics Data Management and Analysis -- Visualization, inspection and interpretation of shotgun proteomics identification results -- Tandem mass spectrum sequencing: an alternative to database search engines in shotgun proteomics -- Protein Inference -- Modification Site Localization in Peptides -- Quantification -- Bioinformatics Tools for the Analysis of Proteomics Data -- Useful Web Resources -- Top-Down Mass Spectrometry: Proteomics to Proteoforms -- Protocol for Standardizing High-to-Moderate Abundance Protein Biomarker Assessments through an MRM-with-Standard-Peptides Quantitative Approach -- Posttranslational Modifications (PTMs) analysis -- Protein-Protein Interaction -- Structural Analysis -- Introduction to Proteomic-Derived Biomarkers -- Discovery of Candidate Biomarkers -- Statistical Approaches to Candidate Biomarker Panel Selection -- Qualification and Verification of biomarker candidates.
520	3		_aThis volume serves as a proteomics reference manual, describing experimental design and execution. The book also shows a large number of examples as to what can be achieved using proteomics techniques. As a relatively young area of scientific research, the breadth and depth of the current state of the art in proteomics might not be obvious to all potential users. There are various books and review articles that cover certain aspects of proteomics but they often lack technical details. Subject specific literature also lacks the broad overviews that are needed to design an experiment in which all steps are compatible and coherent. The objective of this book was to create a proteomics manual to provide scientists who are not experts in the field with an overview of: 1. The types of samples can be analyzed by mass spectrometry for proteomics analysis. 2. Ways to convert biological or ecological samples to analytes ready for mass spectral analysis. 3. Ways to reduce the complexity of the proteome to achieve better coverage of the constituent proteins. 4. How various mass spectrometers work and different ways they can be used for proteomics analysis 5. The various platforms that are available for proteomics data analysis 6. The various applications of proteomics technologies in biological and medical sciences This book should appeal to anyone with an interest in proteomics technologies, proteomics related bioinformatics and proteomics data generation and interpretation. With the broad setup and chapters written by experts in the field, there is information that is valuable for students as well as for researchers who are looking for a hands on introduction into the strengths, weaknesses and opportunities of proteomics
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER
650		7	_aProteínas _0comprobar BNE19900977845 _2embne _9139861
700	1		_aMirzaei, Hamid. _eeditor literario _9101576 _0Local
700	1		_aCarrasco, Martin. _eeditor literario _91093 _0comprobar BNE19900007210
830		0	_aAdvances in Experimental Medicine and Biology _x0065-2598 _v919 _0http://id.loc.gov/authorities/names/n42001229 _9133153
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-41448-5zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319414485
907			_a.b12981266 _b10-10-17 _c08-03-17
998			_am _a_alco _a_vill _b05-07-17 _cm _dz _ek _feng _ggw _h0
945			_aQP551 .M634 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11603100 _z06-04-17
999			_c88122 _d88122 _x1