000			03201nam a22003855i 4500
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007			cr nn 008mamaa
008			161107s2016 gw | s |||| 0|eng d
020			_a9783319403083
024	7		_a10.1007/978-3-319-40308-3 _2doi
040			_aES-MaUEC
050		4	_aQP801.H5 _bH578 2016 EB
245	1	0	_aHistamine Receptors : _bPreclinical and Clinical Aspects _cedited by Patrizio Blandina, Maria Beatrice Passani.
260			_aCham _bSpringer International Publishing _bImprint: Humana Press _c2016.
300			_a1 recurso en línea (XIV, 373 p.) _b111 ilustraciones, 52 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aThe Receptors _v28
505	0		_aMolecular aspects of histamine receptors -- Genetic polymorphisms in the histamine receptor family -- The role of the histamine H4 receptor in asthma and atopic dermatitis -- Identification and roles of zebrafish histamine receptors -- Histamine H3r antagonists: from scaffold hopping to clinical candidates -- Clinical significance of histamine H1 receptor gene expression and drug action of antihistamines -- Histamine and its receptors as a module of the biogenic amine diseasome -- Histaminergic regulation of blood-brain barrier activity -- Histamine function in nervous systems -- Heterogeneity of histaminergic neurons -- Modulation by histamine H3 receptors of neurotransmitter release in the basal ganglia -- Interaction of brain histaminergic and dopaminergic systems -- Histamine H1 Receptor Occupancy in Human Brain Measured by Positron Emission Tomography -- Modulation of memory consolidation and extinction by brain histamine -- Histamine and appetite.
520			_aA comprehensive and detailed overview of the current state of preclinical research on histamine and histamine receptors. Part of the book focuses on novel approaches to the study of histamine receptors such as polymorphism, genetic linkage, and computational analysis, and on the use of new histaminergic ligands in diseases such as asthma and dermatitis. Several chapters will be devoted to the role of histamine in the control of homeostatic and behavioral responses such as the sleep-wake cycle, regulation of the blood brain barrier, food intake, alertness, itch, and memory formation and consolidation.
650		7	_aCompuestos orgánicos _2embne _9680805
700	1		_aBlandina, Patrizio _eeditor literario _0Local _9101560
700	1		_aPassani, Maria Beatrice. _eeditor literario _9101561 _0Local
830		0	_aThe Receptors _v28 _9133208
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-40308-3zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319403083
907			_a.b12981175 _b10-10-17 _c08-03-17
942			_2lcc _cLE
945			_aQP801.H5 H578 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i1160301x _z06-04-17
988			_aEBOOK, EBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0