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008			161012s2016 ne | s |||| 0|eng d
020			_a9789402409215
040			_aES-MaUEC
050		4	_aQR185.8.C95 _bR448 2016 EB
082	0	4	_a616.079
090			_aQR185.8.C95 _bR448 2016
245	1	0	_aRegulation of Cytokine Gene Expression in Immunity and Diseases _cedited by Xiaojing Ma
260			_aDordrecht _bSpringer Netherlands _c2016
300			_a1 recurso en línea (VIII, 225 p.) 23 il., 22 il. col.
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
338			_aonline resource _bcr _2rdacarrier
490	1		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v941
505	0		_aRegulation of IFN-Þ expression -- Regulation of The interleukin-1 family -- Regulation of IL-4 Expression in Immunity and Diseases -- Regulation of IL-6 in immunity and diseases -- Regulation of Interleukin-10 Expression -- Regulation of Interleukin-12 Production in Antigen-Presenting Cells -- Regulation of Interleukin-17 production -- Regulation of interleukin-23 expression in health and disease -- Regulation and immune function of IL-27 -- The immunobiology of Interleukin-35 and its regulation and gene expression.
520			_aThis book explores the major cytokines, such as IL-1 and IFN-Þ, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presenting cutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation. .
942			_2lcc _cLE
988	0	0	_aEBOOK, EBSPRINGER
650		7	_aMedicina _0comprobar BNE19900959047 _2embne _9405021
650		7	_9162770 _aExpresión génica _0comprobar BNE20040069432 _2embne
650		7	_aInmunología _0comprobar BNE19900958507 _2embne _9138330
700	1		_aMa, Xiaojing. _eeditor literario _9100698 _0Local
830		0	_aAdvances in Experimental Medicine and Biology _x0065-2598 _v941 _9133153
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-024-0921-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9789402409215
907			_a.b12960329 _b10-10-17 _c21-11-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gne _h0
945			_aQR185.8.C95 R448 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11616325 _z30-06-17
999			_c86754 _d86754 _x1