000			04556nam a22004215i 4500
001			86699
003			ES-MaUEC
005			20230207040610.0
007			cr nn 008mamaa
008			160105s2016 ne | s |||| 0|eng d
020			_a9789400764163
040			_aES-MaUEC
050		4	_aRA1255 _b.V46 2016 EB
082	0	4	_a615.19
245	1	0	_aVenom genomics and proteomics _cedited by P. Gopalakrishnakone, Juan J. Calvete
250			_a1st ed.
260			_aDordrecht _bSpringer _c2016
300			_a1 recurso en línea (81 ilustraciones, 65 ilustraciones en color)
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aToxinology
505	0		_aDeadly Innovations: Unraveling the Molecular Evolution of Animal Venoms -- Squamate Reptile Genomics and Evolution -- Venoms of Colubrids -- Phylogenetics of Scorpions of Medical Importance -- Scorpion Venom Gland Transcriptomics and Proteomics: An Overview -- Brown Spider Venom: The Identification and Biotechnological Potential of Venom Toxins -- Venom Toxins of Fire Ants -- The Platypus: A Venomous Mammal -- Structure-Function Relationship of Modular Domains of P-III Class -- Snake Venom Metalloproteinases -- Biological Activities and Assays of the Snake Venom Metalloproteinases (SVMPs) -- Three-Dimensional Structures and Mechanisms of Snake Venom Serine Proteinases, Metalloproteinases, and Phospholipase A2s -- Structure-Function Relationship in Heterodimeric Neurotoxin PLA2s from Viperidae Snakes Inhabiting Europe, South America, and Asia -- Snake Venom Phospholipase A2: Evolution and Diversity. - Automated Mass Fingerprinting of Venoms in Nanogram Range: Review of Technology -- Snake Venom Peptidomics -- Snake Venom Proteopeptidomics: What Lies Behind the Curtain -- Shotgun Approaches for Venom Analysis -- Purinergic Mechanisms of Prey Acquisition by Venomous Organisms -- Applications of Snake Toxins in Biomedicine -- Industrial Production and Quality Control of Snake Antivenoms
520			_aThis volume provides the reader with recent advances in the fields of molecular toxinology, the biotechnological applications of venom toxins, and antivenom production. The content of the twenty chapters of Venom Genomics and Proteomics illustrates not only the enormous progress made since the implementation of omics technologies in the field of toxinology, but one also realizes the road still ahead to reach a holistic view of venomous systems. Advancement in high-throughput technologies in the field of venomics has resulted in the ability to generate comprehensive venom profiles for many species. However, research on snake genomes is still in its infancy, although such studies are eagerly awaited to gain insights into the evolutionary history of snake venom proteins, including the mechanisms that originated venom and the regulation of toxin expression. Fortunately, this objective is also at the reach of current omic technologies. Therefore it would not be unrealistic to predict a bright near future to the field of molecular toxinology. Venom Genomics and Proteomics covers research into the venom of scaled reptiles (lizards and snakes), scorpions, spiders, ants and platypuses. Special consideration is given to a number of observations made in the area of snake venom and in the application of advanced genomics and proteomics techniques on a variety of venom samples. The final chapters give some insight into the potential clinical uses of venom derivatives and into the importance and challenges faced in the production and quality control of antivenoms
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER
650		7	_aAnimales venenosos _9138523 _0comprobar BNE19900960858 _2embne
650		7	_aTecnología farmacéutica _0comprobar BNE20030698632 _2embne _9161127
700	1		_aGopalakrishnakone, P. _eeditor literario _0Local _994194
700	1		_aCalvete, Juan J. _eeditor literario _947230
830		0	_aToxinology _9133854
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-007-6416-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9789400764163
907			_a.b12959777 _b10-10-17 _c21-11-16
998			_am _a_alco _a_vill _b30-05-17 _cm _dz _eb _feng _gne _h0
945			_aRA1255 .V46 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11601024 _z06-04-17
999			_c86699 _d86699 _x1