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020 _a9784431560500
040 _aES-MaUEC
050 4 _aQP363
_b.D46 2016 EB
082 0 4 _a612.8
245 0 0 _aDendrites :
_bDevelopment and Disease
_cedited by Kazuo Emoto, Rachel Wong, Eric Huang, Casper Hoogenraad
260 _aTokyo
_bSpringer Japan
_c2016
300 _a1 recurso en línea (VII, 608 p.)
_b104 ilustraciones, 86 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aPart 1 Introduction -- 1 Introduction -- Part 2 Basic biology of dendrites -- 2 Cytoskeletal organization actin -- 3 Cytoskeletal organization microtubules -- 4 Membrane trafficking mechanisms: -endo/exocytosis -- 5 Synapse to nucleus signaling -- 6 Ultrastructural methods -- 7 Bioimaging of dendritic signaling -- Part 3 Patterning dendritic architecture of neurons and their populations -- 8 Self-avoidance -- 9 Dendritic tiling -- 10 Mosaics and lamination -- 11 Modifying dendritic structure after function -- Part 4 Cellular and molecular control of dendrite development and maintenance -- 12 Molecular control of dendrite development -- 13 Sensory-dependent regulation of dendritic morphology -- 14 Dendrite maintenance -- Part 5 Synapse formation onto dendrites -- 15 Molecular assembly of excitatory synapses -- 16 Localizing receptors and channels across the dendritic arbor -- 17 Synaptic adhesion molecules -- 18 Balancing excitatory and inhibitory inputs -- 19 Assembly and reassembly of synapses -- Part 6 Dendrites in disease -- 20 Dendrite development in autism and autism-related disorders -- 21 Dendrite degeneration in Frontotemporal dementia -- 22 Dendrite degeneration and Glaucoma
520 _aStudies in human patients and animal models of disease suggest a strong correlation between defects in dendrite development and common neurological disorders such as autism. Much of this book is thus dedicated toward highlighting recent advances in our understanding of the cellular and molecular mechanisms that regulate the development and maintenance of dendrites, a crucial component of neurons. The book begins by presenting the current state of knowledge on the building blocks or cell biology of dendrites. Mechanisms that sculpt the stereotypic architecture of dendritic arbors and shape their connectivity are also discussed, along with recent work describing how dendritic organization and connectivity are perturbed in disease. A unique aspect of the book is its exploration of diverse neuronal cell types across vertebrates and invertebrates, allowing a comparison of mechanisms across distinct circuits and species. The book comprises six parts, which cover the major advances in the field: Part 1, Introduction; Part 2, Basic Biology of Dendrites; Part 3, Patterning Dendritic Architecture of Neurons and Their Populations; Part 4, Cellular and Molecular Control of Dendrite Development and Maintenance; Part 5, Synapse Formation onto Dendrites; and Part 6, Dendrites in Disease. The book offers an excellent point of entry for students interested in neuroscience, as well as for clinicians
710 2 _aSpringerLink (Online service)
_0Local
_9106996
942 _2lcc
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988 _aEBOOK, EBSPRINGER
650 7 _aNeuronas
_9144348
_0comprobar BNE19912602347
_2embne
650 7 _aSistema nervioso
_0comprobar BNE19900960162
_2embne
_9138462
650 7 _aDendritas
_9158502
_0comprobar BNE20011336946
_2embne
700 1 _aEmoto, Kazuo
_eeditor literario
_9100469
_0Local
700 1 _aWong, Rachel
_eeditor literario
_9100470
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700 1 _aHuang, Eric
_eeditor literario
_9100471
_0Local
700 1 _aHoogenraad, Casper
_eeditor literario
_0Local
_9100472
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-56050-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9784431560500
907 _a.b12958967
_b10-10-17
_c21-11-16
998 _am
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_b08-06-17
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