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_aQP363 _b.D46 2016 EB |
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_aDendrites : _bDevelopment and Disease _cedited by Kazuo Emoto, Rachel Wong, Eric Huang, Casper Hoogenraad |
| 260 |
_aTokyo _bSpringer Japan _c2016 |
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| 300 |
_a1 recurso en línea (VII, 608 p.) _b104 ilustraciones, 86 ilustraciones en color |
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_aTexto (visual) _btxt _2rdacontent |
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_arecurso electrónico _bcr _2rdacarrier |
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| 505 | 0 | _aPart 1 Introduction -- 1 Introduction -- Part 2 Basic biology of dendrites -- 2 Cytoskeletal organization actin -- 3 Cytoskeletal organization microtubules -- 4 Membrane trafficking mechanisms: -endo/exocytosis -- 5 Synapse to nucleus signaling -- 6 Ultrastructural methods -- 7 Bioimaging of dendritic signaling -- Part 3 Patterning dendritic architecture of neurons and their populations -- 8 Self-avoidance -- 9 Dendritic tiling -- 10 Mosaics and lamination -- 11 Modifying dendritic structure after function -- Part 4 Cellular and molecular control of dendrite development and maintenance -- 12 Molecular control of dendrite development -- 13 Sensory-dependent regulation of dendritic morphology -- 14 Dendrite maintenance -- Part 5 Synapse formation onto dendrites -- 15 Molecular assembly of excitatory synapses -- 16 Localizing receptors and channels across the dendritic arbor -- 17 Synaptic adhesion molecules -- 18 Balancing excitatory and inhibitory inputs -- 19 Assembly and reassembly of synapses -- Part 6 Dendrites in disease -- 20 Dendrite development in autism and autism-related disorders -- 21 Dendrite degeneration in Frontotemporal dementia -- 22 Dendrite degeneration and Glaucoma | |
| 520 | _aStudies in human patients and animal models of disease suggest a strong correlation between defects in dendrite development and common neurological disorders such as autism. Much of this book is thus dedicated toward highlighting recent advances in our understanding of the cellular and molecular mechanisms that regulate the development and maintenance of dendrites, a crucial component of neurons. The book begins by presenting the current state of knowledge on the building blocks or cell biology of dendrites. Mechanisms that sculpt the stereotypic architecture of dendritic arbors and shape their connectivity are also discussed, along with recent work describing how dendritic organization and connectivity are perturbed in disease. A unique aspect of the book is its exploration of diverse neuronal cell types across vertebrates and invertebrates, allowing a comparison of mechanisms across distinct circuits and species. The book comprises six parts, which cover the major advances in the field: Part 1, Introduction; Part 2, Basic Biology of Dendrites; Part 3, Patterning Dendritic Architecture of Neurons and Their Populations; Part 4, Cellular and Molecular Control of Dendrite Development and Maintenance; Part 5, Synapse Formation onto Dendrites; and Part 6, Dendrites in Disease. The book offers an excellent point of entry for students interested in neuroscience, as well as for clinicians | ||
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_aDendritas _9158502 _0comprobar BNE20011336946 _2embne |
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_aEmoto, Kazuo _eeditor literario _9100469 _0Local |
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_aWong, Rachel _eeditor literario _9100470 _0Local |
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_aHuang, Eric _eeditor literario _9100471 _0Local |
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_aHoogenraad, Casper _eeditor literario _0Local _9100472 |
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_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-56050-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
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