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003			ES-MaUEC
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008			160602s2016 ja s 000 0 eng d
020			_a9784431560333
040			_aES-MaUEC
050		4	_aQP552.C42 _bC33 2016 EB
082	0	4	_a571.6
245	0	4	_aThe Cadherin Superfamily : _bKey Regulators of Animal Development and Physiology _cedited by Shintaro T Suzuki, Shinji Hirano
260			_aTokyo _bSpringer Japan _c2016
300			_a1 recurso en línea (XII, 428 p.) _b76 ilustraciones, 74 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aForeword -- Preface -- Part I Overview -- 1 Introduction -- 2 Evolution of Cadherins and Associated Catenins -- Part II Classical Cadherins -- 3 Classical Cadherins -- 4 Structure and Function of Cadherin Extracellular Regions -- 5 Regulation of Cadherin-Catenin Biology by Mechanical Force and Phosphorylation -- 6 Cooperative Roles of Nectins with Cadherins in Physiological and Pathological Processes -- Part III Atypical Cadherins -- 7 Desmosomal Cadherins -- 8 Clustered Protocadherins -- 9 The Non-clustered Protocadherins -- 10 Seven-Pass Transmembrane Cadherin CELSRs, and Fat4 and Dchs1 Cadherins: From Planar Cell Polarity to Three-Dimensional Organ Architecture -- 11 Various Atypical Cadherins: T-Cadherin, RET, Calsyntenin, and 7-D Cadherin -- Part IV Cadherins in Tissues and Diseases -- 12 Cadherins in Neural Development -- 13 Cadherins in the Auditory Sensory Organ -- 14 Cadherins in Cancer -- 15 Cadherin-Related Diseases -- BM Index
520			_aThis book presents an overview of the entire field of cadherin research and provides the current basic concept of cadherins. Cadherins have been widely accepted as key regulators of animal development and physiological functions, and it also has become clear that they play essential roles in various human diseases. With contributions by leading scientists, the book covers various aspects of the cadherin superfamily including the history of cadherin research, basic properties of classical cadherins as well as non-classical cadherins, cadherin-associated proteins, and the roles of cadherins in health and diseases. In addition, the book presents some contradictory results and important unanswered questions, and the authors propose their working hypotheses or future directions, to inspire future studies. This volume enables graduate students and young researchers to learn the basics and gain a comprehensive image of the cadherin superfamily, and experts in the field will easily find various topics of interest in relevant areas of study. Additionally, a list of cadherin-related diseases is included for quick reference to cadherins in human diseases
650	0	7	_aProteínas _2embne _9139861
700	1		_aSuzuki, Shintaro T. _eeditor literario _9100467 _0Local
700	1		_aHirano, Shinji _eeditor literario _0Local _9100468
710	2		_aSpringerLink (Online service) _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-56033-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9784431560333
907			_a.b12958955 _b10-10-17 _c21-11-16
942			_2lcc _cLE
945			_aQP552 .C42 C33 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11600421 _z06-04-17
988			_aEBOOK, EBSPRINGER
998			_am _a_alco _a_vill _b08-06-17 _cm _dz _eu _feng _gja _h4