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020 _a9784431560159
040 _aES-MaUEC
050 4 _aQP552.L42
_bC2 2016 EB
082 0 4 _a616.079
245 1 0 _aC-Type Lectin Receptors in Immunity
_cedited by Sho Yamasaki
250 _a1st ed.
264 1 _aTokyo
_bSpringer Japan
_c2016
300 _a1 recurso en línea (VI, 215 páginas)
_b29 ilustraciones, 6 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aPart 1 ITAM-coupled Activating Receptors -- 1 Dectin-2 in anti-microbial immunity and homeostasis -- 2 The function of Mincle as a danger sensor -- 3 The DAP12-Associated Myeloid C-type Lectin 5A (CLEC5A) -- Part 2 HemITAM-bearing Receptors -- 4 Dectin-1 (CLEC7A, BGR, CLECSF12) -- 5 DNGR-1, an F-actin-binding C-type lectin receptor involved in cross-presentation of dead cell-associated antigens by dendritic cells -- 6 C-type lectin-like receptor 2 (CLEC-2) -- Part 3 ITIM-bearing Receptors -- 7 Dendritic cell immunoreceptor (DCIR): An ITIM-harboring C-type lectin receptor -- 8 Regulation and Function of the Inhibitory C-type Lectin Clec12A/MICL -- Part 4 Other receptors and related topics -- 9 DC-SIGN in infection and immunity -- 10 LOX-1 and immunity -- 11 MGL/CD301 as a unique C-type lectin expressed on dendritic cells and macrophages -- 12 Structural aspects of C-type lectin receptors -- 13 The Ligands of C-Type Lectins.
520 _aThe book presents the latest findings on C-type lectin receptors, focusing on individual receptors and their signaling. In recent years there have been great advances in the understanding of the function of these receptors as a newly emerging family of pattern-recognition receptors (PRRs) for pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Comprising four parts: ITAM-coupled Activating Receptors; HemITAM-bearing Receptors; ITIM-bearing Receptors; and Other Receptors and Related Topics, this comprehensive review covers a broad range of C-type lectin receptors. The updated information on C-type lectin receptors and their ligands provided will appeal to a wide readership, from basic immunologists to physicians and surgeons. In addition, sections on novel drug development make this a valuable resource for pharmaceutical scientists.
650 7 _aLectinas
_9666048
_2embne
700 1 _aYamasaki, Sho.
_eeditor literario
_9100464
_0Local
_0http://id.loc.gov/authorities/names/n2016185011
_1http://viaf.org/viaf/162145909952227020269
710 2 _aSpringerLink (Online service)
_0Local
_0http://id.loc.gov/authorities/names/no2005046756
_1http://viaf.org/viaf/148105729
_9106996
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-56015-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9784431560159
907 _a.b1295892x
_b10-10-17
_c21-11-16
942 _2lcc
_cLE
945 _aEBOOK EB
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988 0 0 _aEBOOK, EBSPRINGER, GOBI_sep2018
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