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003			ES-MaUEC
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008			160330s2016 ja | s |||| 0|eng d
020			_a9784431559665
040			_aES-MaUEC _bspa
050		4	_aQH588.S83 _bH86 2016 EB
082	0	4	_a571.6
245	1	0	_aHuman iPS Cells in Disease Modelling _cedited by Keiichi Fukuda
264		1	_aTokyo _bSpringer Japan _c2016
300			_a1 recurso en línea (VII, 99 páginas) _b13 ilustraciones, 12 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aChapter 1 Recent Improvements and Emerging Issues in iPSC Generation for the Modeling of Disease -- Chapter 2 Cardiomyopathy -- Chapter 3 Modelling Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy with Patient-specific iPSCs -- Chapter 4 Cardiac Arrhythmia Modelling Using iPS Cells -- Chapter 5 iPSC Disease Modeling of Laminopathies -- Chapter 6 Hematological Disorders -- Chapter 7 Inherited Metabolic Disorders of the Liver. .
520			_aHuman iPS cells have a great potential to be cell sources for regenerative medicine because of the promise of infinite self-renewal and the capability to differentiate into multiple cell types. This book focuses on another great potential of human iPS cells, which is the establishment of human disease models using patient-specific iPS cells. Human iPS cells can be easily obtained from a patient�s somatic cells and provide the entire information on the patient�s genome. Accordingly, we can generate disease models for inheritable diseases in cell culture dishes using iPS cells. This is a quite new technique but holds tremendous potential for our increased understanding of pathogenesis, and will then be the basis for novel drug development industries. All the authors are leading researchers in this field and they have reported many kinds of patient-derived iPS cells. In this book, they introduce the aspects that could be recapitulated in terms of disease modelling as well as further innovative findings such as novel pathogenetic insights and novel therapies. .
650		7	_aCélulas madre _2embne _9160528
700	1		_aFukuda, Keiichi _eeditor literario _0Local _0http://id.loc.gov/authorities/names/nr2005003967 _1http://viaf.org/viaf/12261633 _9100456
710	2		_aSpringerLink (Online service) _0Local _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-55966-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9784431559665
907			_a.b12958888 _b10-10-17 _c21-11-16
942			_2lcc _cLE
945			_aEBOOK EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11615904 _z30-06-17
988	0	0	_aEBOOK, EBSPRINGER, GOBI_sep2018
988			_aEbook_one2one
998			_aSI _a_alco _a_vill _b10/2018 _cm _dz _ek _feng _gja _h0
999			_c86610 _d86610 _x1