000			03312nam a22003855i 4500
001			86287
003			ES-MaUEC
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007			cr nn 008mamaa
008			160902s2016 gw | s |||| 0|eng d
020			_a9783319427409
040			_aES-MaUEC
050		4	_aRC270.8 _b2016 EB
082	0	4	_a614.5999
245	1	0	_aTargeting Autophagy in Cancer Therapy _cedited by Jin-Ming Yang
264		1	_aCham _bSpringer International Publishing _c2016
300			_a1 recurso en línea (VII, 141 páginas) _b12 ilustraciones, 10 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aCurrent Cancer Research _x2199-2584
505	0		_aAutophagy as a Therapeutic Target in Cancer.-Autophagy in Cancer Cells vs Cancer Tissues: two different stories -- Small-Molecule Regulators of Autophagy as Potential Anti-Cancer Therapy -- Regulation of autophagy by microRNAs: Implications in cancer therapy -- Targeting PI3-kinases in modulating autophagy and anti-cancer therapy -- Adult and Cancer Stem Cells:Perspectives on Autophagic Fate Determinations and Molecular Intervention -- Role of autophagy in tumor progression and regression.
520			_aThis volume will detail the current state and perspectives of autophagy-based cancer therapy. Covering a wide range of topics, it will include an overview of autophagy as a therapeutic target in cancer, autophagy modulators as cancer therapeutic agents, implications of micro-RNA-regulated autophagy in cancer therapy, modulation of autophagy through targeting PI3 kinase in cancer therapy, targeting autophagy in cancer stem cells, and roles of autophagy in cancer immunotherapy. In addition, the volume will review applications of system biology and bioinformatics approaches to discovering cancer therapeutic targets in the autophagy regulatory network. The volume will be beneficial for a variety of basic and clinical scientists, including cancer biologists, autophagy researchers, pharmacologists, and clinical oncologists who wish to delve more deeply into this field of cancer research. This volume will be the first book to focus solely on autophagy as a target in cancer therapy. As well, it will comprehensively discuss the roles of autophagy in most currently available cancer treatments.
650		7	_aCáncer _xInvestigación _2embne _9182523
650		7	_aCiencias biomédicas _2embne _9143729
700	1		_aYang, Jin-Ming. _eeditor literario _999897 _0Local _0http://id.loc.gov/authorities/names/n2017181504 _1http://viaf.org/viaf/5514148814308145330003
710	2		_aSpringerLink (Online service) _0Local _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-42740-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319427409
907			_a.b12955656 _b10-10-17 _c21-11-16
942			_2lcc _cLE
945			_aEBOOK EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i1161531x _z30-06-17
988			_aSpringer_Medicine_2016
998			_aSI _a_alco _a_vill _b10/2018 _cm _dz _ef _feng _ggw _h0
999			_c86287 _d86287 _x1