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020 _a9783319350981
024 7 _a10.1007/978-3-319-35098-1
_2doi
040 _aES-MaUEC
050 4 _aRC280.R38
_bA38 2016 EB
082 0 4 _a614.5999
245 0 0 _aAdvances in Respiratory Cancerogenesis
_cedited by Mieczyslaw Pokorski
250 _a1st ed.
264 1 _aCham
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (VIII, 87 p.) :
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aAdvances in Experimental Medicine and Biology
_x0065-2598
_v911
505 0 _aChapter 1. The Role of Dysregulated MicroRNA Expression in Lung Cancer -- Chapter 2. Laryngeal Cancer: 12-Year Experience of a Single Center -- Chapter 3. Polymorphisms of Selected DNA Repair Genes and Lung Cancer in Chromium Exposure -- Chapter 4. Associations of CYP1A2 Polymorphisms with the Risk Haplotypes in Lung Cancer in the Slovak Population -- Chapter 5. Diagnostic Yield of Endobronchial Ultrasound Guided Transbronchial Needle Aspiration in Patients with Mediastinal Lymph Node Enlargement. - Chapter 6. The Effect on Cognition of Mitochondrial Respiratory System Proteins in Peripheral Blood Mononuclear Cells in the Course of Lung Cancer -- Chapter 7. Lung Cancer and Multiple Neoplasms: a Retrospective Analysis -- Chapter 8. Humoral Immune Response against Neural Antigens and its Effects on Cognition in Lung Cancer Patients -- Chapter 9. Active Case Finding Among Homeless People as a Means of Reducing the Incidence of Pulmonary Tuberculosis in General Population -- Chapter 10. Cryptogenic Organizing Pneumonia: IL-1, IL-6, IL-8, and TGF- 1 Serum Concentrations and Response to Clarithromycin Treatment.
520 3 _aLung cancer is the leading cause of mortality worldwide, with a low survival rate. Carcinogenesis generally requires a constellation of entwined steps, involving both innate cellular and environmental factors. This book shares the updated knowledge on the origin and development of cancer through genotypic changes which upset the physiological balance between cell proliferation, differentiation, growth control, and apoptosis. The emphasis is put on the role of microRNA proteins involved in the cellular processes above outlined. Cognitive changes, related to dysregulated cellular mechanisms in cancer cells, as yet unchartered area of research, also are tackled. A better understanding of the molecular and cellular biology of lung cancer is the key source of breakthroughs in the diagnosis and prognosis, and finding more effective therapies that target specific mutations. The book provides a source of current facts and trends in clinical research and practice. It will be of interest to clinicians, researchers, and other medical professionals.
710 2 _aSpringerLink (Online service)
_0Local
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942 _2lcc
_cLE
988 _aEBOOK, EBSPRINGER
650 7 _aAparato respiratorio
_xCáncer
_9246057
_0comprobar BNE19973664526
_2embne
650 7 _aCarcinogénesis
_0comprobar BNE19923478372
_2embne
_9146492
700 1 _aPokorski, Mieczyslaw
_0no2012119971
_eeditor literario
_948437
830 0 _aAdvances in Experimental Medicine and Biology
_x0065-2598
_v911
_9133153
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-35098-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783319350981
907 _a.b12953635
_b28-10-17
_c21-11-16
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