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020 _a9783319339139
040 _aES-MaUEC
050 4 _aRM315
_b.T736 2016 EB
082 0 4 _a612.8
090 _aRM315
_b.T736 2016
245 1 0 _aTranslational Neuropsychopharmacology
_cedited by Trevor W Robbins, Barbara J Sahakian
260 _aCham
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (XII, 498 p.)
_b124 ilustraciones, 92 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aCurrent Topics in Behavioral Neurosciences
_x1866-3370
_v28
505 0 _aTranslational mouse models of autism; Advancing towards pharmacological therapeutics -- Translatable and back-translatable measurement of impulsivity and compulsivity; convergent and divergent processes -- Translational models of gambling-related decision-making -- Translational research on nicotine dependence -- The need for treatment-responsive translatable biomarkers in alcoholism research -- On the road to translation for PTSD treatment: theoretical and practical considerations of the use of human models of conditioned fear for drug development -- Translational approaches targeting reconsolidation -- Translational assessment of reward and motivational deficits in psychiatric disorders -- Affective biases in humans and animals. Robinson -- Locomotor profiling from the rodents to the clinic and back again -- Animal models of sensori-motor gating in schizophrenia: Are they still relevant? -- Attention and the cholinergic system: relevance to schizophrenia -- Attentional-set-shifting across species -- Relating Translational Neuroimaging and Amperometric Endpoints: Utility for Neuropsychiatric Drug Discovery -- Cognitive translation using the rodent touchscreen test approach -- The Paired Associates Learning (PAL) Test: 30 years of CANTAB Translational Neuroscience From Laboratory to Bedside in Dementia Research -- Translational approaches to experimental medicine.
520 _aThis book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine. .
710 2 _aSpringerLink (Online service)
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988 0 0 _aEBOOK, EBSPRINGER
650 7 _aMedicina
_0comprobar BNE19900959047
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650 7 _aNeurociencias
_0comprobar BNE20012490612
_2embne
_9158907
650 7 _aFarmacología
_0comprobar BNE19900953030
_2embne
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700 1 _aRobbins, Trevor W.
_eeditor literario
_999459
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700 1 _aSahakian, Barbara J.
_eeditor literario
_999460
_0Local
830 0 _aCurrent Topics in Behavioral Neurosciences
_x1866-3370
_v28
_9133305
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-33913-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783319339139
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_b10-10-17
_c21-11-16
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