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008			160926s2016 gw | s |||| 0|eng d
020			_a9783319338262
040			_aES-MaUEC
050		4	_aRA1199.4.A46 _bV355 2016 EB
082	0	4	_a615.19
090			_aRA1199.4.A46 _bV355 2016
245	1	0	_aValidation of Alternative Methods for Toxicity Testing _cedited by Chantra Eskes, Maurice Whelan
260			_aCham _bSpringer International Publishing _c2016
300			_a1 recurso en línea (XX, 407 p.) _b44 ilustraciones, 40 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v856
505	0		_aIntroduction -- Validation in support of internationally harmonised OECD Test Guidelines for assessing the safety of chemicals -- Regulatory acceptance of alternative methods in the development and approval of pharmaceuticals -- Validation of alternative in vitro methods to animal testing: concepts, challenges, processes and tools -- Practical aspects of designing and conducting validation studies involving multi-study trials -- Validation of computational methods -- Implementation of New Test Methods into Practical Testing -- Pathway Based Toxicology and Fit-for-Purpose Assays -- Evidence-based toxicology -- Validation of transcriptomics-based in vitro methods -- Ensuring the quality of stem cell-derived in vitro models for toxicity testing -- Validation of bioreactor and human-on-a-chip devices for chemical safety assessment -- Integrated approaches to testing and assessment -- International harmonization and cooperation in the validation of alternative methods -- Evolving the principles and practice of validation for new alternative approaches to toxicity testing. .
520			_a.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988	0	0	_aEBOOK, EBSPRINGER
650		7	_aMedicina _0comprobar BNE19900959047 _2embne _9405021
650		7	_aBiología molecular _0comprobar BNE19900968373 _2embne _9139103
650		7	_aTecnología farmacéutica _0comprobar BNE20030698632 _2embne _9161127
700	1		_aEskes, Chantra _eeditor literario _0Local _999452
700			_aWhelan, Maurice _eeditor literario _0Local _999453
830		0	_aAdvances in Experimental Medicine and Biology _x0065-2598 _v856 _9133153
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-33826-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319338262
907			_a.b12953234 _b10-10-17 _c21-11-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aRA1199.4.A46 V355 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11614845 _z30-06-17
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