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008			160518s2016 gw | s |||| 0|eng d
020			_a9783319321899
040			_aES-MaUEC
050		4	_aRB153 _b.B567 2016 EB
082	0	4	_a579.3
245	1	0	_aBiophysics of Infection _cedited by Mark C Leake
260			_aCham _bSpringer International Publishing _c2016
300			_a1 recurso en línea (IX, 362 p.) _b87 ilustraciones, 76 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v915
505	0		_aThe Biophysics of Infection -- Single-molecule observation of DNA replication repair pathways in E. coli -- Investigating the swimming of microbial pathogens using digital holography -- What is the �minimum inhibitory concentration� (MIC) of pexiganan acting on Escherichia coli? � A cautionary case study -- Evolution of drug resistance in bacteria -- Using Biophysics to Monitor the Essential Proton motive Force in Bacteria -- The Type I restriction enzymes as barriers to horizontal gene transfer: determination of the DNA target sequences recognised by Livestock-Associated Methicillin Resistant Staphylococcus aureus Clonal Complexes 133/ST771 and 398 -- Biomechanical analysis of infectious biofilms -- Designing a single-molecule biophysics tool for characterizing DNA damage for techniques that kill infectious pathogens through DNA damage effects -- Bacterial Surfaces: Front Lines in Host-Pathogen Interaction -- Biophysical approaches to bacterial gene regulation by riboswitches -- Bugs on a slippery plane: Understanding the motility of microbial pathogens with mathematical modelling -- Transcription regulation and membrane stress management in enterobacterial pathogens -- How biophysics may help us understand the flagellar motor of bacteria which cause infections. -- Mechanics of bacterial cells and initial surface colonisation -- Neutron reflectivity as a tool for physics-based studies of model bacterial membranes -- Mechanisms of Salmonella Typhi host-restriction -- Insights into biological complexity from simple foundations -- Force spectroscopy in studying infection -- Imaging Immunity in Lymph Nodes: Past, Present and Future -- Bacterial pathogen biofilms: studying and manipulating evolution.
520			_aThis book describes modern biophysical techniques that enable us to understand and examine dynamic processes of infection at the molecular level. Cutting-edge research articles, laboratory protocols, case studies and up-to-date reviews cover topics such as single-molecule observation of DNA replication repair pathways in E. coli; evolution of drug resistance in bacteria; restriction enzymes as barriers to horizontal gene transfer in Staphylococcus aureus; infectious and bacterial pathogen biofilms; killing infectious pathogens through DNA damage; bacterial surfaces in host-pathogen interactions; bacterial gene regulation by riboswitches; transcription regulation in enterobacterial pathogens; the bacterial flagellar motor; initial surface colonization by bacteria; Salmonella Typhi host restrictions; as well as monitoring proton motive force in bacteria; microbial pathogens using digital holography; mathematical modelling of microbial pathogen motility; neutron reflectivity in studying bacterial membranes; force spectroscopy in studying infection and 4D multi-photon imaging to investigate immune responses. The focus is on the development and application of complex techniques and protocols at the interface of life sciences and physics, which increase the physiological relevance of biophysical investigations.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988	0	0	_aEBOOK, EBSPRINGER
650	0	4	_9495993 _aCiencias de la vida
650		7	_aInmunología _0comprobar BNE19900958507 _2embne _9138330
650		7	_9405049 _aMicrobiología médica _0comprobar BNE19900963008 _2embne
700	1		_aLeake, Mark C. _eeditor literario _999184 _0Local
830		0	_aAdvances in Experimental Medicine and Biology _x0065-2598 _v915 _9133153
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-32189-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319321899
907			_a.b12951687 _b10-10-17 _c21-11-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aRB153 .B567 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11594469 _z06-04-17
999			_c85890 _d85890 _x1