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020 _a9783319319735
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050 4 _aQP252
_b.M654 2016 EB
082 0 4 _a571.8
245 1 0 _aMolecular Mechanisms of Cell Differentiation in Gonad Development
_cedited by Rafal P Piprek
264 1 _aCham
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (XII, 434 páginas)
_b52 ilustraciones, 48 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aResults and Problems in Cell Differentiation
_x0080-1844
_v58
505 0 _aEarly Development of the Gonads � Origin and Differentiation of the Somatic Cells of the Genital Ridges -- The formation and migration of primordial germ cells in mouse and man -- The Gonadal Supporting Cell Lineage and Mammalian Sex Determination: the Differentiation of Sertoli and Granulosa Cells -- Mesonephric cell migration into the gonads and vascularization are processes crucial for testis development -- Origin and Differentiation of Androgen-producing Cells in the Gonads -- Germ cell commitment to oogenic versus spermatogenic pathway - the role of retinoic acid -- Ovarian Folliculogenesis -- Control of oocyte growth and development by intercellular communication within the follicular niche -- Biology of the Sertoli cell in the Fetal, Pubertal and Adult Mammalian Testis -- Mechanisms Regulating Spermatogonial Differentiation -- Stem cells in mammalian gonads -- A Role of microRNAs in Cell Differentiation during Gonad Development -- The Battle of the Sexes: Human Sex Development and its Disorders -- Methods for the study of gonadal development.
520 _aThis book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.
650 7 _aEndocrinología
_0comprobar BNE19900971669
_2embne
_9139372
700 1 _aPiprek, Rafal P.
_eeditor literario
_999148
_0Local
830 0 _aMcGraw-Hill's AccessMedicine
_9134597
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-31973-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783319319735
907 _a.b12951511
_b10-10-17
_c21-11-16
942 _2lcc
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_z30-06-17
988 0 0 _aEBOOK, EBSPRINGER
998 _aSI
_b07/2018
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