000			03400nam a22003735i 4500
710	2		_aSpringerLink (Online service) _0Local _9106996
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003			ES-MaUEC
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007			cr nn 008mamaa
008			160628s2016 gw | s |||| 0|eng d
020			_a9783319312514
040			_aES-MaUEC
050		4	_aQP114.C44 _bC373 2016 EB
082	0	4	_a571.6
245	1	0	_aCardiomyocytes : _bActive Players in Cardiac Disease _cedited by Klaus-Dieter Schlüter
264		1	_aCham _bSpringer International Publishing _c2016
300			_a1 recurso en línea (XV, 278 páginas) _b40 ilustraciones, 13 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aCardiomyocytes: Function and Regeneration -- 1.Ways to study the biology of cardiomyocytes -- 2.Cardiomyocytes: Function and Regeneration -- 3.Excitation-contraction coupling of cardiomyocytes -- 4.Cardiac metabolism and energetic control -- 5.Endogenous mechanisms for regulating myocardial contractility -- Cardiomyocytes in ageing, disease, and protection -- 6.Growth regulation of cardiomyocytes: Control of cell size and its role in cardiac hypertrophy -- 7.Protein Degradation in Cardiomyocytes � Target Proteins and clinical consequences -- 8.Ischemia and Reperfusion -- 9.Mechanisms of cardiac cell death -- 10.Oxidative stress and nitrosative stress.
520			_aThis book summarizes our current understanding about the biology and patho-biology of cardiomyocytes and depicts common techniques for the study of these cells. The book is divided into two parts; the first part provides insight into role and function of cardiomyocytes under normal conditions and describes embryogenesis and differentiation, in the second part the role of cardiomyocytes in aging and disease is discussed and cellular responses under stress conditions illustrated. Cardiomyocytes represent the main mass of the heart, and cellular malfunction directly modifies heart function leading to subsequent heart failure. As such, cardiomyocytes are causative involved in the main reasons of heart failure, such as post-infarct remodeling, hypertensive heart disease, idiopathic heart failure, and interactions with other co-morbidities such as diabetes. On the other hand, cardiomyocytes are necessarily target of therapy. Therefore, a precise understanding of cardiomyocytes biology is a pre-requisite for proper disease treatment and evidence based medicine. The book is written for cell biologists, pharmacologists and biomedical researchers specialized in cardiac and vascular biology.
650		7	_aCorazón _xEnfermedades _0comprobar BNE19901075238 _2embne _9169667
700	1		_aSchlüter, Klaus-Dieter. _eeditor literario _999035 _0Local
830		0	_aMcGraw-Hill's AccessMedicine _9134597 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-31251-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319312514
907			_a.b12950865 _b10-10-17 _c21-11-16
942			_2lcc _cLE
945			_aEBOOK EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11614420 _z30-06-17
988	0	0	_aEBOOK, EBSPRINGER
998			_aSI _b07/2018 _cm _dz _ea _feng _gxxu _h0