000 04255nam a22003855i 4500
001 85746
003 ES-MaUEC
005 20230207040525.0
007 cr nn 008mamaa
008 160510s2016 gw | s |||| 0|eng d
020 _a9783319306544
040 _aES-MaUEC
050 4 _aRC267
_b.C363 2016
082 0 4 _a614.5999
245 1 0 _aCancer and Zebrafish :
_bMechanisms, Techniques, and Models
_cedited by David M Langenau
260 _aCham
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (XII, 552 páginas)
_b85 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aAdvances in Experimental Medicine and Biology
_x0065-2598
_v916
505 0 _aPart 1. Powers Of The Zebrafish Model -- 1. Uncharted Waters: Zebrafish Cancer Models Navigate A Course for Oncogene Discovery -- 2. The Toolbox for Conditional Zebrafish Cancer Models -- 3. Approaches to Inactivate Genes in Zebrafish -- 4. Tumor Suppressors in Zebrafish: From Tp53 To Pten and Beyond -- 5. Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish -- 6. Genomic Approaches To Zebrafish Cancer -- 7. Transcriptomic Analyses in Zebrafish Cancer Models for Global Gene Expression and Pathway Discovery -- 8. Zebrafish Discoveries in Cancer Epigenetics -- 9. Lymphatics, Cancer and Zebrafish -- 10. In Vivo Imaging of Cancer in Zebrafish -- 11. Imaging Cancer Angiogenesis and Metastasis in A Zebrafish Embryo Model -- 12. Allograft Cancer Cell Transplantation in Zebrafish -- 13. The Zebrafish Xenograft Platform: Evolution of A Novel Cancer Model and Preclinical Screening Tool -- 14. Automation of Technology for Cancer Research -- Part 2. Cancer Models in Fish -- 15. Zebrafish Models Of Human Leukemia: Technological Advances and Mechanistic Insights -- 16. Zebrafish Rhabdomyosarcoma -- 17. Baiting for Cancer: Using The Zebrafish as A Model in Liver And Pancreatic Cancer -- 18. How Zebrafish Are Helping Us To Target Colorectal Cancer -- 19. Zebrafish Melanoma -- 20. Neuroblastoma and Its Zebrafish Model -- 21. Zebrafish Germ Cell Tumors -- 22. Malignant Peripheral Nerve Sheath Tumors -- 23. Xiphophorus and Medaka Cancer Models.
520 3 _aThis volume focuses on defining the unique attributes of using the zebrafish cancer model for discovering important pathways and potential drug targets for the treatment of human cancers. Using the zebrafish model, the volume explores oncogene and tumor suppressor discovery, chemical genetic approaches, genomics, epigenetics, cancer imaging, and cell transplantation. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish cancer models, including T cell leukemia, rhabdomyosarcoma, liver and pancreatic cancer, melanoma, neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. A chapter is also dedicated to the development and utilization of other piscine models of cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and cancer, providing a much needed resource on the powerful attributes of the zebrafish model system.
710 2 _aSpringerLink (Online service)
_0Local
_9106996
942 _2lcc
_cLE
988 _aEBOOK, asignarmaterias , EBSPRINGER
650 7 _aMedicina
_0comprobar BNE19900959047
_2embne
_9405021
650 7 _aCáncer
_xInvestigación
_0comprobar BNE19901364217
_2embne
_9182523
700 1 _aLangenau, David M.
_eeditor literario
_998925
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-30654-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783319306544
907 _a.b12950245
_b10-10-17
_c21-11-16
998 _am
_a_alco
_a_vill
_b - -
_cm
_dz
_e-
_feng
_ggw
_h0
945 _aRC267 .C363 2016 EB
_g1
_ieBOOK
_j0
_lmae
_o-
_pEUR0.00
_q-
_r-
_sb
_t15
_u0
_v0
_w0
_x0
_y.i11593362
_z06-04-17
999 _c85746
_d85746
_x1