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020 _a9783319290737
040 _aES-MaUEC
050 4 _aQP623.8.P75
_bR537 2016 EB
082 0 4 _a611.01816
082 0 4 _a599.935
245 1 0 _aRNA Processing :
_bDisease and Genome-wide Probing
_cedited by Gene W Yeo
260 _aCham
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (XIII, 326 p.)
_b37 ilustraciones, 34 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aAdvances in Experimental Medicine and Biology
_x0065-2598
_v907
505 0 _aExperimental and computational considerations in the study of RNA binding protein-RNA interactions -- Genome-wide approaches for RNA structure probing -- Tethered function assays as tools to elucidate the molecular roles of RNA binding proteins -- Single molecule approaches in RNA-protein interactions -- RNA dynamics in the control of circadian rhythm -- Roles of RNA binding proteins and post-transcriptional regulation in driving male germ cell development in the mouse -- Regulation of stem cell self-renewal and oncogenesis by RNA binding proteins -- Controlling the editor: the many roles of RNA binding proteins in regulating A-to-I RNA editing -- Mutations in splicing factors and cancer -- Regulation of tissue-specific alternative splicing: C. elegans as a model system -- RNA Granules and Diseases�A Case Study of Stress Granules in ALS and FTLD -- Post-translational modifications and RNA-binding proteins.
520 _aRibonucleic acid (RNA) binding proteins currently number in the thousands and defects in their function are at the heart of diseases such as cancer and neurodegeneration. RNA binding proteins have become implicated in the intricate control of surprisingly diverse biological settings, such as circadian rhythm, stem cell self-renewal, oncogenesis and germ cell development. This book surveys a range of genome-wide and systems approaches to studying RNA binding proteins, the importance of RNA binding proteins in development, cancer and circadian rhythm. .
710 2 _aSpringerLink (Online service)
_0Local
_9106996
942 _2lcc
_cLE
988 0 0 _aEBOOK, EBSPRINGER
650 7 _aMedicina
_0comprobar BNE19900959047
_2embne
_9405021
650 7 _aGenética humana
_0comprobar BNE19900986777
_2embne
_9140562
650 0 7 _aCiencias biomédicas
_0LocalX
_2embne
_9143729
700 1 _aYeo, Gene W.
_eeditor literario
_985067
_0Local
830 0 _aAdvances in Experimental Medicine and Biology
_x0065-2598
_v907
_9133153
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-29073-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783319290737
907 _a.b12948135
_b10-10-17
_c21-11-16
998 _am
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