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008			160606s2016 gw | s |||| 0|eng d
020			_a9783319283050
040			_aES-MaUEC
050		4	_aRC280.B7 _b2016 EB
245	0	0	_aRadiobiology of Glioblastoma : _bRecent Advances and Related Pathobiology _cedited by Luigi Pirtoli, Giovanni Luca Gravina, Antonio Giordano
260			_aCham _bSpringer International Publishing _bImprint _bHumana Press _c2016
300			_a1 recurso en línea (XX, 305 p.) 49 il., 39 il. col.
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aCurrent Clinical Pathology _x2197-781X
520			_aThis text properly considers the most recent and relevant advances in molecular RB of GB, taking into account the related topics of pathobiology, and underscores the most promising translational perspectives from the preclinical to the clinical domain. Section I (From Bedside to Bench) discusses conditions associated with RT resistance of GB and the consequent RB hints, technology improvements intended to overcome RT-resistance of GB, mathematical modeling of RB parameters from clinical studies, the present impact of molecular prognostic factors in therapy of GB, and RT tolerance of normal brain. Section II (Preclinical Research and Pathobiology Topics) presents the traditional and mechanistic/molecular approaches to RB of GB, genetic and epigenetic studies on GB, issues of cell-death pathways, stem-like cells, invasiveness, tumor microenvironment, hypoxia, mi-RNA manipulations, and nanoparticle technology. Section III (Translational Perspectives) presents RB issues related to molecular profiling and classification of GB as frames of reference for clinical studies, translational perspectives of gene therapy, evolving protocols based on pre-clinical data and large data-bases and ontologic models. Radiobiology of Glioblastoma: Recent Advances and Related Pathobiology will be of great value to pathologists, medical oncologists, radiation oncologists as well as basic researchers and clinical investigators
942			_2lcc _cLE
650		7	_aCerebro _xTumores _xDiagnóstico _9207398 _0comprobar BNE19930544250 _2embne
700	1		_aPirtoli, Luigi. _eeditor literario _998389 _0Local
700	1		_aGravina, Giovanni Luca _eeditor literario _0Local _998390
700	1		_aGiordano, Antonio. _eeditor literario _926701 _0comprobar BNE19982551126
830		0	_aCurrent Clinical Pathology _x2197-781X _9133628
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-28305-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319283050
907			_a.b12947167 _b10-10-17 _c21-11-16
988			_aSpringer_Medicine_2016
998			_am _a_alco _a_vill _b13-03-17 _cm _dz _ek _feng _ggw _h0
945			_aRC280.B7 R335 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11590774 _z06-04-17
999			_c85438 _d85438 _x1