000			03216nam a22003375i 4500
001			85412
003			ES-MaUEC
005			20230207040510.0
007			cr nn 008mamaa
008			160210s2016 gw | s |||| 0|eng d
020			_a9783319280981
040			_aES-MaUEC
050		4	_aQH601 _b.B364 2016 EB
100	1		_aBanfalvi, Gaspar _0Local _986222
245	1	0	_aPermeability of Biological Membranes _cby Gaspar Banfalvi
250			_a1st ed.
260			_aCham _bSpringer International Publishing _c2016
300			_a1 recurso en línea (XI, 263 p.) _b94 ilustraciones, 52 ilustraciones col.
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
520			_aThis book deals with biological membranes, focuses on permeabilization and pays particular attention to reversible permeabilization to maintain the viability and physiological conditions of the cells. Selective permeability of biological membranes also known as semipermeability, partial permeability or differential permeability allows molecules to diffuse, pass by passive and active or by other types of transport processes mediated by proteins. The first chapter of the book deals with the composition of biological membranes, characterizes cellular membranes of prokaryotic, eukaryotic cells, membranes of cellular organelles and the function of biological membranes. The second chapter provides an overview of bilayer permeability, selectivity of permeabilization and cellular transport processes. Chapter 3 overviews different cell manipulations that aim to make cells permeable while maintaining not only the structural but also the functional integrity of cells. The last chapter deals with applications, particularly with reversible permeabilization to study macromolecular (DNA, RNA, poly-ADP ribose) biosynthetic processes, replication, gene expression, visualization of replicons, intermediates of chromosome condensation, genotoxic chromatin changes, upon treatment with heavy metals and different types of irradiation. The interdisciplinary aspects of the book contribute to the understanding of the structure of nucleic acids, replicative intermediates, Okazaki fragments, RNA primer mechanism, subphases of replication and repair synthesis, replicons, gene expression, chromosome condensation generated a wealth of information that will attract a wide readership. The natural audience engaged in DNA research, including genetics, cell and molecular biology, chemistry, biochemistry, medicine, pharmacy will find essential material in the book. .
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER
650		7	_aMembranas celulares _0comprobar BNE19901012138 _2embne _9142266
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-28098-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319280981
907			_a.b12946904 _b10-10-17 _c21-11-16
998			_am _a_alco _a_vill _b22-03-17 _cm _dz _ei _feng _ggw _h0
945			_aQH601 .B364 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11590579 _z06-04-17
999			_c85412 _d85412 _x1