000			03385nam a22003855i 4500
001			85358
003			ES-MaUEC
005			20230207040507.0
007			cr nn 008mamaa
008			160229s2016 gw | s |||| 0|eng d
020			_a9783319276472
040			_aES-MaUEC
050		4	_aRC280.M6 _b2016 EB
082	0	4	_a617.6
245	1	0	_aTargeting Oral Cancer _cedited by Andrew M Fribley
250			_a1st ed.
260			_aCham _bSpringer International Publishing _c2016
300			_a1 recurso en línea (X, 302 páginas) _b38 ilustraciones, 2 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aEpidemiology and Management: Epidemiology -- Emerging Role of HPV -- Management of Oral Cancer. Development and Biomarkers: Molecular Progression and Signaling -- Stem Cells and Tumor Development -- Prognostic/Predictive Biomarkers -- EIF4e as Biomarker and Target. Breaking Developments and New Drug Discovery: Current Clinical Trials -- Emerging Drug Targets -- Targeting the UPR -- Targeting Meditators of Coagulation -- Resveratrol Pre-Sensitizing -- Academic High Throughput Drug Discovery.
520	3		_aThis book provides research-oriented care providers with up-to-date information on the oral cancer patient population, the ways in which we are treating them, and the scientific approaches being pursued in order to improve survival and reduce treatment-related morbidity. The text is organized into three sections covering epidemiology and management, cancer development and biomarkers, and breaking developments and novel approaches for drug discovery. The first section includes discussion of the emerging role of human papillomavirus in oral cancer and explains the surgical, chemotherapy, and radiation approaches to treatment. Aspects such as molecular progression and signaling, the role of cancer stem cells in tumor development, and the value of various biomarkers are then examined. The final section is devoted to the latest advances and covers, among other topics, current clinical trials, emerging drug targets, and targeting of the unfolded protein response and of mediators of coagulation. Recent decades have witnessed a significant increase in the number of deaths worldwide from cancers of the oral cavity, pharynx, and oropharynx. Targeting Oral Cancer will be an excellent resource for practitioners and researchers and will hopefully assist in the urgent quest to improve screening and prevention, diagnosis, and treatment approaches.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
650		7	_aOdontología _0comprobar BNE19900960285 _2embne _9138473
650		7	_aOncología _0comprobar BNE19900969554 _2embne _9139207
700	1		_aM. Fribley, Andrew. _eeditor literario _998267 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-27647-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319276472
907			_a.b12946369 _b10-10-17 _c21-11-16
988			_aSpringer_Medicine_2016
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aRC280.M6 T374 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11590154 _z06-04-17
999			_c85358 _d85358 _x1