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001			85337
003			ES-MaUEC
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007			cr nn 008mamaa
008			160322s2016 gw | s |||| 0|eng d
020			_a9783319275116
040			_aES-MaUEC
082	0	4	_a572.6
050		4	_aQP301 _b.G769 2016 EB
245	1	0	_aGrowth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease _cedited by Jason White, Gayle Smythe
250			_a1st ed.
264		1	_aCham _bSpringer International Publishing _c2016
300			_a1 recurso en línea (IX, 192 páginas) _b19 ilustraciones, 14 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v900
505	0		_aHepatocyte Growth Factor and Satellite Cell Activation -- Cytokine mediated control of muscle stem cell function -- The role of Leukemia inhibitory factor receptor signaling in skeletal muscle growth, injury and disease -- Function of Membrane-Associated Proteoglycans in the Regulation of Satellite Cell Growth -- The TGF-Ý signalling network in muscle development, adaptation and disease -- Adipokines in healthy skeletal muscle and metabolic disease -- Role of growth factors in modulation of the microvasculature in adult skeletal muscle.
520			_aThis book describes the diverse roles that growth factors and cytokines play in skeletal muscle. The extracellular environment has profound effects on the biology of skeletal muscle. The soluble portion of this environment includes a rich milieu of growth factors and cytokines which have been shown to regulate virtually all facets of the response of skeletal muscle to external stimuli, whether it be exercise induced metabolic shifts, remodeling in response to trauma or loading of the ongoing pathology associated with neuromuscular disease. The chapters included in this work illustrate growth factors that directly affect skeletal muscle cells and those which influence non-muscle cells that contribute to the biology of skeletal muscle as a whole tissue. The current state of the art, with the advent of systems biology, allows for the delineation of signaling networks which are regulated by suites of growth factors. This is in stark contrast to early more traditional studies, which only examined the effects of isolated growth factors on the activity of skeletal muscle precursor cells in tissue culture. The work presented in this volume ranges from reviewing and analyzing the roles of individual growth factors in detail, to the complex interplay of multiple soluble factors in the control of muscle functional, and dysfunctional states. The material covered in this volume will particularly suit readers from a range of research fields spanning general muscle biology and physiology, and those working on diseases and conditions affecting skeletal muscle both directly and indirectly.
710	2		_aSpringerLink (Online service) _0Local _9106996
830		0	_aMcGraw-Hill's AccessMedicine
942			_2lcc _cLE
988	0	0	_aEBOOK, EBSPRINGER
650		7	_aFisiología humana _0comprobar BNE19900979803 _2embne _9140024
700	1		_aWhite, Jason. _eeditor literario _935161 _0comprobar BNE20031204209
700	1		_aSmythe, Gayle. _eeditor literario _998233 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-27511-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319275116
907			_a.b12946151 _b10-10-17 _c21-11-16
945			_aEBOOK EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11613592 _z30-06-17
998			_aSI _b07/2018 _cm _dz _ea _feng _gxxu _h0
999			_c85337 _d85337 _x1