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020			_a9783319274492
040			_aES-MaUEC
050		4	_aRA1211 _b.T736 2016
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245	1	0	_aTranslational Toxicology : _bDefining a New Therapeutic Discipline _cedited by Claude L Hughes, Michael D Waters
250			_a1st ed.
260			_aCham _bSpringer International Publishing _bImprint _bHumana Press _c2016
300			_a1 recurso en línea (XV, 380 páginas) _b32 ilustraciones, 12 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aMolecular and Integrative Toxicology _x2168-4219
505	0		_aI.Introduction -- The Opportunity to Translate Developmental Toxicology into a Therapeutic Discipline -- The Role of Toxicokinetics and Toxicodynamics in Developmental and Translational Toxicology -- II.Toxicant Modes of Action and Biomarkers -- Mutational Effects -- Ligand-Mediated Toxicology: Characterization and Translational Prospects -- Effects of Environmentally Acquired Heavy Metals and Nutrients on the Epigenome and Phenotype -- Fetal Imaging and Effects of Exposures on Growth and Function -- III.Developmental Risks of Exposures and Potential Translational Toxicology Therapeutics -- Ovarian Toxicity of Environmental Contaminants: 50 Shades of Grey -- The zToxicy Effects of a Perinatal Obesogenic Environment: Maternal Obesity and Impacts on Future Generations -- The Role of Environmental Exposures in Preterm Birth -- The Impact of Environmental Stressors on DNA Methylation, Neurobehavioral Development and Chronic Physical Aggression: Prospects for Early Protective Interventions -- Coffee Health Effects from Early Fetal Development through Childhood and Adolescence.
520	3		_aBringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology�a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and potential translational toxicology therapeutics. The result is a compelling application of developmental toxicology in a new therapeutic discipline that is destined to become part of standard medical practice. Translational Toxicology: Defining a New Therapeutic Discipline is an essential text for regulatory authorities, scientists, and physicians who are concerned with environmental exposures, public health, nutrition, and pharmaceutical research and development. Basic science, epidemiological, and clinical investigators will also find this book a significant resource.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, asignarmaterias , EBSPRINGER
650		7	_aMedicina _0comprobar BNE19900959047 _2embne _9405021
650		7	_aFarmacología _0comprobar BNE19900953030 _2embne _9137893
700	1		_aHughes, Claude L. _eeditor literario _998214 _0Local
700	1		_aWaters, Michael D. _eeditor literario _998215 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-27449-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319274492
907			_a.b12946059 _b10-10-17 _c21-11-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aRA1211 .T736 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11589887 _z06-04-17
999			_c85327 _d85327 _x1