000			03165nam a22003975i 4500
001			85284
003			ES-MaUEC
005			20230207040503.0
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008			160404s2016 gw | s |||| 0|eng d
020			_a9783319271118
040			_aES-MaUEC
050		4	_aQP620 _b.M635 2016
082	0	4	_a572.84
245	1	0	_aModified Nucleic Acids _cedited by Kazuhiko Nakatani, Yitzhak Tor
260			_aCham _bSpringer International Publishing _c2016
300			_a1 recurso en línea (X, 276 páginas) _b162 ilustraciones, 62 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aNucleic Acids and Molecular Biology _x0933-1891 _v31
505	0		_aEmissive 5-Substituted Uridine Analogues -- Fluorescent purine nucleosides and their applications -- Thiazole orange-tethered nucleic acids and ECHO probes for fluorometric detection of nucleic acids -- Synthetic wavelength-shifting fluorescent probes of nucleic acids -- DNA Assisted Multichromophore Assembly -- Polymerase Synthesis of Base-Modified DNA -- Photo-cross-linking Reaction in Nucleic Acids � Chemistry and Applications -- Site-Directed Spin Labeling for EPR Studies of Nucleic Acids -- Non-Covalent Modification of Double Stranded DNA at the Mismatch and Bulged Site -- 2',4'-Bridged Nucleic Acids for Targeting Double-Stranded DNA -- Specific Recognition of Single Nucleotide by Alkylating Oligonucleotides and Sensing of 8-oxoguanine -- Genetic alphabet expansion by unnatural base pair creation and its application to high affinity DNA aptamers.
520	3		_aThis book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, asignarmaterias , EBSPRINGER
650	0	4	_9495993 _aCiencias de la vida
650	0	4	_9485040 _aIngeniería bioquímica
700	1		_aNakatani, Kazuhiko. _eeditor literario _998141 _0Local
700	1		_aTor, Yitzhak. _eeditor literario _998142 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-27111-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319271118
907			_a.b12945626 _b10-10-17 _c21-11-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aQP620 .M635 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11589486 _z06-04-17
999			_c85284 _d85284 _x1