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020 _a9783319270166
040 _aES-MaUEC
050 4 _aRC271.C5
_b2016 EB
082 0 4 _a616.994
245 1 0 _aManagement of Chemotherapy-Induced Nausea and Vomiting :
_bNew Agents and New Uses of Current Agents
_cedited by Rudolph M Navari
250 _a1st ed.
260 _aCham
_bSpringer International Publishing
_bImprint
_bAdis
_c2016
300 _a1 recurso en línea (VIII, 181 páginas)
_b17 ilustraciones, 9 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _a1. Introduction -- 2. The Physiology and Pharmacology of Nausea and Vomiting Induced by Anti-Cancer Chemotherapy in Humans -- 3. First Generation 5HT-3 Receptor Antagonists -- 4. Second Generation Serotonin (5-HT3) Receptor Antagonist Palonosetron -- 5. The Role of Neurokinin-1 Receptor Antagonists in CINV -- 6. Olanzapine for the prevention of Chemotherapy-Induced Nausea and Vomiting -- 7. Gabapentin for the Prevention of CINV -- 8. Prevention of CINV in Patients Receiving High-Dose Multiple-Day Chemotherapy -- 9. Clinical Management of CINV -- 10. Treatment of Chemotherapy-Induced Nausea -- 11. Conclusions -- 12. Future Directions.
520 3 _aThis book provides a comprehensive review of new agents, a detailed description of new uses of current agents, and an integration of the available agents in clinical practice. A description of a detailed clinical approach provides clinical practitioners with the most up-to-date recommendations for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV) in various clinical settings. CINV is one of the most feared treatment related toxicities. Patient surveys for the past thirty years consistently demonstrate patients� perception of deterioration in quality of life due to chemotherapy treatments. The introduction of the antiemetics, serotonin 5-HT3 receptor antagonists and the neurokinin-1 receptor antagonists, have improved the control of chemotherapy-induced emesis, but the treatment of chemotherapy-induced nausea remains a significant clinical problem. Patients continue to have quality of life issues which prevent normal functioning during active treatment. New agents such as the second generation 5-HT3 receptor antagonist palonosetron and the new neuroknin-1 receptor antagonists rolapitant and netupitant are being introduced into clinical practice, and it is anticipated that these new agents will improve the control of CINV. Agents such as olanzapine (a FDA approved anti-psychotic), gabapentin (a FDA approved neuroleptic), and ginger (a food additive), which have been used primarily for other indications, are now being tested as potential, effective antiemetics. This work represents the first available comprehensive summary that details all new antiemetic agents and, particularly, their clinical role in treating patients; an important reference for practitioners seeking to improve the quality of life of patients undergoing chemotherapy.
710 2 _aSpringerLink (Online service)
_0Local
_9106996
942 _2lcc
_cLE
650 7 _aMedicina
_0comprobar BNE19900959047
_2embne
_9405021
650 7 _aFarmacología
_0comprobar BNE19900953030
_2embne
_9137893
700 1 _aNavari, Rudolph M.
_eeditor literario
_998110
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-27016-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783319270166
907 _a.b1294550x
_b10-10-17
_c21-11-16
988 _aSpringer_Medicine_2016
998 _am
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