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001			85114
003			ES-MaUEC
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007			cr nn 008mamaa
008			160112s2016 gw a s 001 0 eng d
020			_a9783319256160
024	7		_a10.1007/978-3-319-25616-0 _2doi
040			_aES-MaUEC
050			_aRC685.H8 _bH97 2016
082	0	4	_a612.8
245	0	0	_aHypertension and the Brain as an End-Organ Target _cedited by Hélène Girouard
264	1		_aCham _bSpringer International Publishing _c2016
300			_a1 recurso en línea (XIX, 221 p.) _b24 ilustraciones, 20 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aA systematic review of reviews to examine the association between hypertension and cognitive impairments in adults -- Hypertension and age-related cognitive decline -- Hypertension and stroke -- Neuroimaging as a research tool in human essential hypertension -- Cognitive Dysfunction and Dementia in animal models of hypertension -- The effects of hypertension on cerebral artery structure and function, and cerebral blood flow -- Arterial stiffness and the brain -- Endothelium, the blood-brain barrier, and hypertension -- Hypertension and brain inflammation: role of RAS-induced glial activation -- Sex differences in neural regulation of hypertension.
520	3		_aThe first comprehensive overview of the effects of hypertension on the brain. The book discusses not only the relationship between hypertension and stroke, but also the much less studied relationship between hypertension and cognitive decline and neurodegenerative diseases such as Alzheimer's. It seeks to answer two important questions. First, what are the conditions under which hypertension is associated with stroke, cognitive decline, and neurodegenerative disease? And second, what are the biological mechanisms by which hypertension alters brain homeostasis? By looking at the biological mechanisms of these relationships, this book provides insight to neuroscientists and neurologists regarding why anti-hypertension treatments make a big difference in the case of stroke, but have very little impact on cognitive decline and brain aging.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER
650		7	_aHipertensión _0comprobar BNE19900989691 _2embne _9140794
650		7	_aNeurociencias _0comprobar BNE20012490612 _2embne _9158907
650		7	_aNeurología _0comprobar BNE19900967585 _2embne _9139040
700	1		_aGirouard, Hélène _eeditor literario _997831 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-25616-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319256160
907			_a.b12943927 _b10-10-17 _c21-11-16
998			_am _a_alco _a_vill _b29-09-17 _cm _dz _ei _feng _ggw _h0
945			_aRC685.H8 H97 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i1158807x _z06-04-17
999			_c85114 _d85114 _x1