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020 _a9783319251240
040 _aES-MaUEC
050 4 _aQP187
_b.P678 2016
082 0 4 _a612
245 1 0 _aPost-transcriptional Mechanisms in Endocrine Regulation
_cedited by KMJ Menon, Aaron C Goldstrohm
250 _a1st ed.
260 _aCham
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (XIV, 341 páginas)
_b51 ilustraciones, 7 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aMechanisms of post-transcriptional gene regulation -- Post-transcriptional regulation of insulin and insulin like growth factor -- Posttranscriptional regulation of cytokine signaling during inflammatory responses -- Regulation of luteinizing hormone Receptor mRNA expression in the ovary -- Post-transcriptional regulation of steroid hormone receptors�microRNA regulation of endocrine function in the ovary -- Translational control in the germline -- Post-transcriptional regulation of VEGF-A -- Post-transcriptional regulation of prostaglandin biosynthesis -- Translational and post-translational control of leptin production by fat cells -- Post-transcriptional regulation of parathyroid hormone gene expression in health and disease -- Post-transcriptional and post-translational regulation in steroidogenesis -- Post-transcriptional regulation of glucocorticoid function -- Post-transcriptional regulation by brain-derived neurotrophic factor in the nervous system. �.
520 3 _aThis book examines how post-transcriptional mechanisms control endocrine function. This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones. The impacts of these mechanisms on disease and health are covered, providing a novel update to the scientific literature. Post-transcriptional regulatory mechanisms play an essential role in controlling dynamic gene expression. The outcome of this regulation includes control of the amount, timing, and location of protein expression. Regulation is mediated by cis-acting RNA sequences and structures and transacting RNA binding proteins and non-coding RNAs, including microRNAs. Recent advances in characterization of these regulatory factors have revealed enormous regulatory potential.
710 2 _aSpringerLink (Online service)
_0Local
_9106996
942 _2lcc
_cLE
988 _aEBOOK, asignarmaterias , EBSPRINGER
650 7 _aMedicina
_0comprobar BNE19900959047
_2embne
_9405021
650 7 _9162770
_aExpresión génica
_0comprobar BNE20040069432
_2embne
700 1 _aMenon, K.M.J.
_eeditor literario
_997779
_0Local
700 1 _aGoldstrohm, Aaron C.
_eeditor literario
_997780
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-25124-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783319251240
907 _a.b12943617
_b10-10-17
_c21-11-16
998 _am
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