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020			_a9783319250656
040			_aES-MaUEC
050		4	_aQP185 _b.H473 2016
082	0	4	_a572
245	1	0	_aHepatic De Novo Lipogenesis and Regulation of Metabolism _cedited by James M Ntambi
250			_a1st ed.
260			_aCham _bSpringer International Publishing _c2016
300			_a1 recurso en línea (XI, 305 páginas) _b35 ilustraciones, 5 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aTranscriptional Regulation of De Novo Lipogenesis in Liver -- The Molecular Basis of Hepatic De Novo Lipogenesis in Insulin Resistance -- Regulation of Hepatic Metabolism by the Mechanistic Target of Rapamycin -- FoxO1: A Conductor of Insulin Signaling to Glucose and Lipid Metabolism -- Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease -- Role of the Endocannabinoid System in Hepatic Lipogenesis -- Role of Lipogenesis and Lipid Desaturases in Non-Alcoholic Fatty Liver Disease -- Lipid Droplet Proteins and Lipid Metabolism -- Influence of Gut Microbiota on Hepatic Lipogenesis and Disease Pathogenesis -- Hepatic Lipogenesis: Nutritional Control and Pathophysiological Relevance -- Metabolic Rhythm of Hepatic Lipogenesis: Regulation and Roles in Metabolism -- Monounsaturated Fatty Acid Mediated Liver-adipose Tissue Crosstalk and Metabolic Regulation -- Adipose Tissue DNL and Its Role in Metabolic Homeostasis -- The Lipogenic Effect of Insulin Revisited -- Index.�.
520	3		_aThe liver is the largest solid vital organ in mammals that supports other organ in the body in some facet.� This book synthesizes all the primary and relevant metabolic information that one needs to review to understand the complex and diverse role of the liver in metabolism. With the current epidemic of metabolic diseases, it is of immediate importance to understand the contribution of the liver in health and its role in the development of impaired metabolic regulation. This book covers the many studies that have unmasked important roles that proteins expressed in the liver play in the development of or protection from metabolic diseases. One of the major metabolic functions of the liver is to carry out de novo lipogenesis, which is the metabolic pathway that allows the conversion of excess carbohydrates into fatty acids. The process of de novo lipogenesis is covered in depth within this volume. �The book is an important contribution to the vast literature and ongoing research on liver function.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, asignarmaterias , EBSPRINGER
650	0	4	_9495993 _aCiencias de la vida
650		7	_aNutrición _2embne _9138371
700	1		_aNtambi, James M. _eeditor literario _997769 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-25065-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319250656
907			_a.b12943538 _b10-10-17 _c21-11-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aQP185 .H473 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11587738 _z06-04-17
999			_c85075 _d85075 _x1