000 03518nam a22004095i 4500
001 85002
003 ES-MaUEC
005 20230207040450.0
007 cr nn 008mamaa
008 151224s2016 gw | s |||| 0|eng d
020 _a9783319241999
040 _aES-MaUEC
050 4 _aRS431.P37
_bA585 2016
082 0 4 _a616.079
245 1 0 _aAntimicrobial Peptides :
_bRole in Human Health and Disease
_cedited by Jürgen Harder, Jens-M Schröder
250 _a1st ed.
260 _aCham
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (VI, 158 páginas)
_b10 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aBirkhäuser Advances in Infectious Diseases
505 0 _aAntimicrobial peptides in cutaneous wound healing -- Antimicrobial peptides as endogenous antibacterials and antivirals at the ocular surface -- Function of antimicrobial peptides in lung innate immunity -- Role of antimicrobial peptides to prevent infections in the kidney and urinary tract -- Antimicrobial peptides in the gut -- Metal sequestration: An important contribution of antimicrobial peptides to nutritional immunity -- Regulation of antimicrobial peptide gene expression by vitamin D -- Dichotomous roles of cationic polypeptides targeting HIV -- Antimicrobial peptides in host-defense: functions beyond antimicrobial activity.
520 3 _aThis book focuses on the importance of human antimicrobial peptides (AMP) in keeping the host healthy and preventing infectious diseases. The first chapters deal with several examples of the role of AMP in different epithelial organs (skin and wound healing, eye, lung, genito-urinary tract, gut), which are exposed to different kinds of infectious microorganisms and as a result produce different patterns of AMP. Examples of the dysregulation of AMP expression and function promoting infections are discussed. The capacity of AMP to restrict the availability of essential metals to bacteria as an efficient antibacterial strategy in nutritional immunity is discussed in the next chapter. Our current understanding of how vitamin D, the sunshine vitamin, influences AMP-expression and how this can affect our health is also addressed. Last but not least, the role of AMP in HIV infection and the immunomodulatory properties of AMP highlight the diverse facets of AMP in host immunity. AMP�s specific functions, including in fighting multi-resistant bacteria, suggest that they may offer therapeutic benefits � a question that is discussed in the final chapter.
710 2 _aSpringerLink (Online service)
_0Local
_9106996
942 _2lcc
_cLE
988 _aEBOOK, asignarmaterias , EBSPRINGER
650 7 _aMedicina
_0comprobar BNE19900959047
_2embne
_9405021
650 7 _aInmunología
_0comprobar BNE19900958507
_2embne
_9138330
700 1 _aHarder, Jürgen
_eeditor literario
_0Local
_997643
700 1 _aSchröder, Jens-M.
_eeditor literario
_997644
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-24199-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783319241999
907 _a.b12942807
_b10-10-17
_c21-11-16
998 _am
_a_alco
_a_vill
_b - -
_cm
_dz
_e-
_feng
_ggw
_h0
945 _aRS431.P37 A585 2016 EB
_g1
_ieBOOK
_j0
_lmae
_o-
_pEUR0.00
_q-
_r-
_sb
_t15
_u0
_v0
_w0
_x0
_y.i11587088
_z06-04-17
999 _c85002
_d85002
_x1