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020 _a9783319240855
040 _aES-MaUEC
050 4 _aRC349.T65
_b2016 EB
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245 1 0 _aOCT in Central Nervous System Diseases :
_bThe Eye as a Window to the Brain
_cedited by Andrzej Grzybowski, Piero Barboni
260 _aCham
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (VI, 342 páginas)
_b112 ilustraciones, 102 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aIntroduction -- OCT Technique � Past, Present and Future -- Optic Disc Edema -- Compressive Optic Neuropathy -- Multiple Sclerosis -- Parkinson�s Disease -- Alzheimer�s Disease -- Friedreichs Ataxia and More -- �Other Neurological Disorders: Migraine, Neurosarcoidosis, Schizophrenia, Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) -- Hereditary Optic Neuropathies -- Trans Neuronal Retrograde Degeneration -- New OCT Technology in Neuro-Ophthalmology -- OCT and Pharmacological Treatment -- Animal Models in Neuro-Ophthalmology -- OCT in Glaucoma -- OCT in Amblyopia -- Conclusions.
520 3 _aThis book reviews recent important advances in the use of optical coherence tomography (OCT) in order to analyze neurodegeneration within the retina through the quantification of axonal loss. Detailed information is provided on the role of OCT as a promising tool for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. The disorders considered include multiple sclerosis, Parkinson�s disease, Alzheimer�s disease, intracranial hypertension, Friedreich�s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models. As well as being a valuable tool for diagnosis of many retinal diseases and monitoring of surgical and medical treatment, OCT allows study of the retinal nerve fiber layer (RNFL) containing the axons of the retinal ganglion cells, which form the optic nerves, chiasm, and optic tracts. Since retinal axons are nonmyelinated until they penetrate the lamina cribrosa, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. It is for this reason that OCT has been applied in various areas of neurology over the past decade, becoming a hot topic and generating great enthusiasm among neurologists and ophthalmologists. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the zwindow to the brainy.
710 2 _aSpringerLink (Online service)
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650 7 _aMedicina
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650 7 _aRadiología
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700 1 _aGrzybowski, Andrzej
_eeditor literario
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700 1 _aBarboni, Piero
_eeditor literario
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856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-24085-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783319240855
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_b10-10-17
_c21-11-16
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