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020 _a9783319239071
040 _aES-MaUEC
050 4 _aRB155
_b.L664 2016
082 0 4 _a614.5999
245 1 0 _aLong Non-coding RNAs in Human Disease
_cedited by Kevin V Morris
250 _a1st ed.
260 _aCham
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (VIII, 262 páginas) :
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aCurrent Topics in Microbiology and Immunology
_x0070-217X
_v394
505 0 _aUnderstanding the Complex Circuitry of lncRNAs at the X-inactivation Center and its Implications in Disease Conditions -- Long Non-coding RNA ANRIL and Polycomb in Human Cancers and Cardiovascular Disease -- Form and function of exosome associated long non-coding RNAs in cancer -- Long Non-coding RNAs in Lung Cancer -- Pseudogene-expressed RNAs: Emerging roles in gene regulation and disease -- Functional long non-coding RNAs in vascular smooth muscle cells -- Long Non-coding RNAs as Targets and Regulators of Nuclear Hormone Receptors -- Non-coding transcriptional landscape in human aging -- LncRNAs in stress response -- Expression Specificity of Disease-Associated lncRNAs: towards Personalized Medicine. .
520 3 _aThis volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.
710 2 _aSpringerLink (Online service)
_0Local
_9106996
942 _2lcc
_cLE
988 _aEBOOK, asignarmaterias , EBSPRINGER
650 7 _aMedicina
_0comprobar BNE19900959047
_2embne
_9405021
650 7 _aCáncer
_xInvestigación
_0comprobar BNE19901364217
_2embne
_9182523
700 1 _aMorris, Kevin V.
_eeditor literario
_997609
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-23907-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783319239071
907 _a.b12942595
_b10-10-17
_c21-11-16
998 _am
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945 _aRB155 .L664 2016 EB
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