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020 _a9783319232461
040 _aES-MaUEC
050 4 _aQP86
_b2016 EB
082 0 4 _a618.97
082 0 4 _a612.67
245 1 0 _aAdvances in Geroscience
_cedited by Felipe Sierra, Ronald Kohanski
250 _a1st ed.
260 _aCham
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (XXIII, 622 páginas)
_b39 ilustraciones
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aThe Geroscience Hypothesis: Is It Possible to Change the Rate of Aging?: Steven N. Austad -- Etiological Role of Aging in Chronic Diseases: From Epidemiological Evidence to the New Geroscience: Linda P. Fried and Luigi Ferrucci -- The Impact of Aging on Cancer Progression and Treatment: Shenghui He and Norman E. Sharpless -- The Impact of Cancer Treatments on Aging: Changhan Lee and Valter Longo -- Cardiovascular Disease and Aging: Ying Ann Chiao, Edward Lakatta, Zoltan Ungvari, Dao-Fu Dai and Peter Rabinovitch -- The Impact of Aging on Ischemic Stroke: Farida Sohrabji -- Parkinson�s Disease and Aging: Julie K. Andersen -- The Role of Aging in Alzheimer�s Disease: Geoffrey A. Kerchner and Tony Wyss-Coray -- Aging and the Bone-Muscle Interface: Simon Melov and Clifford J. Rosen -- Osteoporosis and Mechanisms of Skeletal Aging: Julie Glowacki and Tamara Vokes -- Osteoarthritis in the Elderly: Richard F. Loeser and Martin Lotz -- Diabetes and Aging: Nicolas Musi and Andrzej Bartke -- Renal Aging and Transplantation: John P. Higgins and Stuart K. Kim -- Asthma and Aging: Nicola A. Hanania and Paula Busse -- Aging in COPD and Idiopathic Pulmonary Fibrosis: Cecilia Sanchez -- Age-Related Macular Degeneration and Vision Impairment: Jayakrishna Ambati and Charles Wright -- HIV and Aging: Parallels and Synergistic Mechanisms Leading to Premature Disease and Functional Decline: Anna Hearps, Katherine Schafer, Kevin High and Alan Landay -- Pain in the Elderly: Roger B. Fillingim, Dennis C. Turk and Robert P. Yezierski -- The Way Forward: Translation: James L. Kirkland.
520 3 _aThis book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or �healthspan.� � The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer�s diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. �It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.
710 2 _aSpringerLink (Online service)
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650 7 _aMedicina
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650 7 _aBiología molecular
_0comprobar BNE19900968373
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700 1 _aSierra, Felipe.
_eeditor literario
_997457
_0Local
700 1 _aKohanski, Ronald
_eeditor literario
_0Local
_997458
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-23246-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
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907 _a.b12941803
_b10-10-17
_c21-11-16
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