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008			150827s2016 gw a s 001 0 eng d
020			_a9783319214344
024	7		_a10.1007/978-3-319-21434-4 _2doi
040			_aES-MaUEC
050		4	_aRM322 _b2016 EB
082	0	4	_a610
100	1		_aEadie, Mervyn J. _0n 50030294 _948495
245	1	0	_aAntiepileptic Drugs and Pregnancy : _bA Guide for Prescribers _cby MJ. Eadie, FJE. Vajda
264		1	_aCham _bSpringer International Publishing _bImprint _bAdis _c2016
300			_a1 recurso en línea (XII, 232 p.) _b24 ilustraciones, 6 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_a1. Introduction -- 2. Antiepileptic drugs and becoming pregnant -- Part I. Antiepileptic Drug Pharmacokinetics in Pregnancy -- 3. Antiepileptic drug disposition and pregnancy -- 4. The older antiepileptic drugs -- 5. Commonly used newer antiepileptic drugs -- 6. Antiepileptic drugs sometimes used in pregnancy -- Part II. Antiepileptic Drugs and the Foetus -- 7. Antiepileptic drugs, epileptic seizures and the foetus -- 8. Antiepileptic drugs and foetal malformations - a possible class effect -- 9. Particular antiepileptic drugs and foetal malformations -- 10. Antiepileptic drugs, cognition and neurodevelopment -- Part III. Antiepileptic Drug use and Pregnancy -- 11. Antiepileptic drug therapy: management issues and pregnancy -- 12. Antiepileptic drugs and pregnancy -- the future.
520	3		_aA description of our current understanding of antiepileptic drug use during pregnancy, this book includes chapters on the impact of seizures on the mother and developing child, changes in maternal physiology during pregnancy and its impact on drug disposition, and the pharmacokinetic differences between the various anti-seizure medications. It also deals with the possible harmful effects of antiepileptic drug exposure during pregnancy on the physical and intellectual development of the fetus. Clinicians have to balance the potential adverse effects of the medicine for the fetus and mother-to-be against the risks that uncontrolled seizures hold for both when treating pregnant women with antiepileptic drugs. Only recently have enough scientific data emerged to provide a rational basis for treatment decisions that take in both aspects. This work provides a single, accessible, and up-to-date resource for busy clinicians.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
650		7	_aAnticonvulsivos _9144280 _0comprobar BNE19912516408 _2embne
650		7	_aObstetricia _0comprobar BNE19900953186 _2embne _9137907
700	1		_aVajda, F. J. E. (Frank J. E.) _0n 85276051 _948496
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-21434-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319214344
907			_a.b12940380 _b28-10-17 _c21-11-16
988			_aSpringer_Medicine_2016
998			_am _a_alco _a_vill _b21-10-17 _cm _dz _eo _feng _ggw _h0
945			_aRM322 .E23 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11584816 _z06-04-17
999			_c84760 _d84760 _x1