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020			_a9783319057989
040			_aES-MaUEC
050		4	_aRJ416.L4 _b2016 EB
082	0	4	_a616.15
245	1	0	_aEtiology of Acute Leukemias in Children _cedited by Juan Manuel Mejía-Aranguré
250			_a1st ed.
260			_aCham _bSpringer International Publishing _c2016
300			_a1 recurso en línea (XIII, 320 p.) _b27 ilustraciones, 24 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_a1. Acute leukemias - An introduction -- 2. Etiology and prevention of acute leukemias in children -- 3. Direct viral leukemogenesis hypothesis -- 4. Etiology of leukemia in children with Down syndrome -- 5. Origin of leukemia in children with Down syndrome -- 6. Model: Susceptibility, exposure and vulnerability period -- 7. Molecular origin of acute leukemias -- 8. When as environmental factor would be considered cause of acute leukemia in children -- 9. Early bone marrow hematopoietic differentiation in acute lymphoblastic leukemia.
520			_aChildhood acute leukemias are one of the main causes of death in children aged 1 to 14 years in some countries; and unfortunately, we have been unable to prevent it. Certainly, a good parcel of it is due to the poor understanding about its etiology. This book aims to describe the most important theories and hypothesis regarding childhood acute leukemia. Written by the most outstanding researchers in the field, this book intends to contribute to a greater understanding of the etiology of this disease. It goes beyond the simple and common analysis of risk factors, which hardly allows us to draw definite conclusions. By addressing the etiology of the disease, discussing from molecular biology until epidemiology and clinical manifestations, this book will guide present and future approaches, contributing for a better clinical management of leukemia in children. The knowledge regarding etiology is a crucial step for a better evaluation, prevention and treatment of a disease. Thus, this book finally intends to provide such knowledge, allowing physicians and practitioners to a better manage of childhood acute leukemias.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
650		7	_aMedicina _0comprobar BNE19900959047 _2embne _9405021
650		7	_9140122 _aHematología _0comprobar BNE19900981064 _2embne
650		7	_aOncología _0comprobar BNE19900969554 _2embne _9139207
700	1		_aMejía-Aranguré, Juan Manuel. _eeditor literario _996764 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-05798-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319057989
907			_a.b12938026 _b10-10-17 _c21-11-16
988			_aSpringer_Medicine_2016
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aRJ416.L4 E856 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11582649 _z06-04-17
999			_c84524 _d84524 _x1