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001			84482
003			ES-MaUEC
005			20240611040139.0
007			cr nn 008mamaa
008			160805s2016 xxu| s |||| 0|eng d
020			_a9781493936496
040			_aES-MaUEC
050		4	_aRC262 _b.P76 2016 EB
082	0	4	_a614.5999
245	1	0	_aProtein Tyrosine Phosphatases in Cancer _cedited by Benjamin G Neel, Nicholas K Tonks
264		1	_aNew York, NY _bSpringer New York _c2016
300			_a1 recurso en línea (VIII, 360 páginas) _b28 ilustraciones, 19 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_a1 Introduction to the PTP Superfamily -- 2 Receptor PTPs in Cancer -- 3 Non-Receptor PTPs in Cancer -- 4 HP2 -- 5 C-PTP -- 6 PTP1B -- 7 PTP-PEST -- 8 Dual Specificity Phosphatases in Cancer -- 9 Phosphatase-dependent roles for PTEN in Cancer -- 10 Phosphatase-independent roles for PTEN in Cancer -- 11 PRL family members in Cancer -- 12 Cdc25 family -- 13 PTPs, metabolism and cancer -- 14 PTPs, metabolism and cancer -- 15 Current status of PTP-based therapeutics -- 16 Summary and Perspective. .
520			_aThis book aims to bridge the gap in understanding how protein-tyrosine phosphatases (PTPs), which carry out the reverse reaction of tyrosine phosphorylation, feature in cancer cell biology. The expertly authored chapters will first review the general features of the PTP superfamily, including their overall structure and enzymological properties; use selected examples of individual PTP superfamily members, to illustrate emerging data on the role of PTPs in cancer; and will review the current status of PTP-based drug development efforts. Protein Tyrosine Phosphatases in Cancer,from renowned researchers Benjamin Neel and Nicholas Tonks, is invaluable reading for researchers in oncology, stem cell signaling,and biochemistry. .
650		7	_aCáncer _xInvestigación _2embne _9182523
700	1		_aNeel, Benjamin G. _eeditor literario _996689 _0Local _0http://id.loc.gov/authorities/names/n93801988 _1http://viaf.org/viaf/43523067
700	1		_aTonks, Nicholas K. _eeditor literario _996690 _0Local _0http://id.loc.gov/authorities/names/n95802907
710	2		_aSpringerLink (Online service) _0Local _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-3649-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9781493936496
907			_a.b12937605 _b10-10-17 _c21-11-16
942			_2lcc _cLE
945			_aEBOOK EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11612654 _z30-06-17
988	0	0	_aEBOOK, EBSPRINGER, GOBI_sep2018
988			_aEbook_one2one
998			_aSI _a_alco _a_vill _b10/2018 _cm _dz _ef _feng _gxxu _h0
999			_c84482 _d84482 _x1