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008			151218s2016 xxu| s |||| 0|eng d
020			_a9781493932283
040			_aES-MaUEC
050		4	_aR857.T55 _bR444 2016
245	1	0	_aRegenerative Medicine for Degenerative Muscle Diseases _cedited by Martin K Childers
250			_a1st ed.
260			_aNew York, NY _bSpringer New York _bImprint _bHumana Press _c2016
300			_a1 recurso en línea (XIII, 336 páginas) _b26 ilustraciones, 23 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aStem Cell Biology and Regenerative Medicine _x2196-8985
505	0		_aPreface -- 1. Regenerative Medicine Approaches to Degenerative Muscle Diseases -- 2. An Overview of rAAV Vector Product Development for Gene Therapy -- 3. Gene Discovery in Congenital Myopathy -- 4. Stem Cell Transplantation for Degenerative Muscle -- 5. Spinal Cord Cellular Therapeutics Delivery:� Device Design Considerations -- 6. Patient Derived Induced Pluripotent Stem Cells Provide a Regenerative Medicine Platform for Duchenne Muscular Dystrophy Heart Failure -- 7. Overview of Chemistry, Manufacturing and Controls (CMC) for Pluripotent Stem Cell-Based Therapies -- 8. Regenerative Rehabilitation: Synergizing Regenerative Medicine Therapies with Rehabilitation for Improved Muscle Regeneration in Muscle Pathologies -- 9. Practical Nutrition Guidelines for Individuals with Duchenne Muscular Dystrophy -- 10. Identifying Beneficial Drug Therapies for Muscle Disease Using Zebrafish -- 11. The Use of miRNAs in Muscle Diseases -- 12 Canine Inherited Dystrophinopathies and Centronuclear Myopathies -- Index.
520	3		_aThis book compiles and explores cutting-edge research in degenerative skeletal disorders, such as Duchenne muscular dystrophy and congenital myopathy, and new stem-cell based therapies and gene replacement therapy. Twelve expertly-authored chapters navigate the nuances of these treatments in an array of contexts and biological systems. The topics covered include: How are urine cells from a patient with Duchenne muscular dystrophy transformed into beating heart cells? What can reprogrammed cells tell us about heart muscle failure? What do gene mutations mean for those born with a muscle disease? How are manufacturing methods applied to human stem cells? Does therapeutic exercise benefit those patients who receive engineered limb muscle? Is there practical advice about nutrition to enhance muscle function for the Duchenne patient? Can microRNAs be useful to regenerate diseased muscle? Regenerative Medicine for Degenerative Muscle Diseases is ideal for scientists and clinicians from varying disciplines in genetics, cell biology, virology, cell-based manufacturing, rehabilitation medicine, nutrition, veterinary medicine and neurosurgery. The reader will see how transformative changes occur in medicine that can powerfully impact the future for patients suffering from inherited disorders affecting muscles of the body, including the heart.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988	0	0	_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650	0	4	_9495993 _aCiencias de la vida
650		7	_aBiotecnología _0comprobar BNE19900991605 _2embne _9140931
650		7	_aCélulas madre _0comprobar BNE20022110396 _2embne _9160528
700	1		_aChilders, Martin K. _eeditor literario _996631 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-3228-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9781493932283
907			_a.b12937253 _b10-10-17 _c21-11-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gxxu _h0
945			_aR857.T55 R444 2016 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11582108 _z06-04-17
999			_c84447 _d84447 _x1