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| 020 | _a9781493929115 | ||
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| 082 | 0 | 4 | _a616.96 |
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_aQR185.8.T24 _bT448 2016 EB |
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| 245 | 1 | 4 |
_aThe Th2 Type Immune Response in Health and Disease : _bFrom Host Defense and Allergy to Metabolic Homeostasis and Beyond _cedited by William C Gause, David Artis |
| 250 | _a1st ed. | ||
| 264 | 1 |
_aNew York, NY _bSpringer New York _c2016 |
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| 300 |
_a1 recurso en línea (XIV, 172 páginas) _b23 ilustraciones en color |
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| 336 |
_aTexto (visual) _btxt _2rdacontent |
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| 337 |
_aelectrónico _bc _2rdamedia |
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| 338 |
_arecurso electrónico _bcr _2rdacarrier |
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| 505 | 0 | _aRegulation and Function of Basophil, Eosinophil and Mast Cell Responses -- Innate lymphoid cells: An Emerging Population in type 2 Inflammation -- Dendritic Cells and Type 2 Inflammation -- Th2 Cell Responses in Immunity and Inflammation Following Helminth Infection -- Regulatory T Cell Control of Type 2 Inflammation -- Developments in the Design of Anti-Helminth Vaccines -- Tissue Remodeling and Repair During Type 2 Inflammation -- Immune Response to Helminth Infections and as Treatment for Autoimmune Disorders -- Type 2 Immunity and Metabolism. | |
| 520 | _aThe type 2 immune response that develops during infectious disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified.� It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL-13, is associated with helminth infections in both humans and mice.� This response is complex and includes effector functions that mediate resistance, contributing to expulsion, and in some cases destruction, of the parasite.� But just as importantly, the type 2 immune response can also mediate tolerance mechanisms, which can mitigate tissue injury as these large multicellular parasites transit through vital organs.� The tolerance mechanisms include both tissue repair and immune regulatory effects. These latter aspects of the helminth-induced type 2 immune response are increasingly recognized as a potential resource that can be mined for the development of novel immunotherapies that may enhance wound healing, control of autoimmune and inflammatory diseases and regulation of metabolic homeostasis.� In this book, leading researchers in this exciting and dynamic field discuss the latest findings and emerging concepts, providing an intellectual framework that can be used as a basis for new discoveries and potentially new treatments for diseases associated with inflammation. | ||
| 710 | 2 |
_aSpringerLink (Online service) _0Local _9106996 |
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| 830 | 0 | _aMcGraw-Hill's AccessMedicine | |
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_aInmunología _2embne _0comprobar BNE19900958507 _9138330 |
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_aGause, William C. _eeditor literario _996598 _0Local |
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_aArtis, David _eeditor literario _0Local _996599 |
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_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-2911-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
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