000			02572nam a22003495i 4500
999			_c82601 _d82601
001			82601
003			ES-MaUEC
005			20230215112851.0
008			160916t2015 ja a s |||1 0|eng d
020			_a9784431544876
040			_aES-MaUEC
050		4	_aRC122.B4 _b2015 EB
082	0	4	_a616.723
245	0	0	_aBehçet's disease : _bfrom genetics to therapies _cedited by Yoshiaki Ishigatsubo
260			_aTokyo _bSpringer _ccop. 2015
300			_a1 recurso en línea (IX, 176 p.) _bil.
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
520			_aThis book, besides reviewing basic and clinical aspects of BehÃ{u00A7}et's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of BehÃ{u00A7}et's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- BehÃ{u00A7}et's disease. BehÃ{u00A7}et's Disease:Â{u01B2}om Genetics to Therapies Â{u0CAF}vides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in BehÃ{u00A7}et's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons.
650	0	7	_aSíndrome de Behçet _0LocalX _2embne _9672746
700	1		_aIshigatsubo, Yoshiaki _eeditor literario _995641 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-54487-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9784431544876
907			_a.b12912414 _b10-10-17 _c10-02-16
942			_2lcc _cLE
945			_aRC122.B4 B44 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11580094 _z06-04-17
988			_aSpringer_Medicine_2015
998			_am _a_alco _a_vill _b16-09-16 _cm _dz _ea _feng _gja _h0