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020 _a9783319225425
040 _aES-MaUEC
050 4 _aRC280.T6
_b2015 EB
082 0 4 _a616.994
245 0 0 _aMedullary Thyroid Carcinoma :
_bBiology, Management, Treatment
_cedited by Friedhelm Raue
250 _a1st ed.
260 _aCham, Switzerland
_bSpringer
_c2015
300 _a1 recurso en línea (VIII, 249 p.) 50 il., 28 il. col.
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aRecent Results in Cancer Research
_x0080-0015
_v204
520 _aThis book offers a comprehensive overview of medullary thyroid carcinoma, both in the more common sporadic form and in the familial form, multiple endocrine neoplasia (MEN) types 2A and 2B. The coverage includes, but is not limited to, molecular biology and genetics, pathology, clinical presentation, imaging techniques, surgical treatment, and follow-up. The role of calcitonin as a highly sensitive and specific tumor marker for the screening, diagnosis, and follow-up of MTC and metastatic disease is described, and the significance of other tumor markers is also considered. With regard to treatment, the use of thyroidectomy is fully discussed, including in children carrying the mutations in the RET proto-oncogene considered causative for MEN 2. Additionally, the value of tyrosine kinase inhibitors as the most effective treatment modality in patients with a large tumor burden or rapid tumor growth, or both, is explained. Medullary Thyroid Carcinoma and Multiple Endocrine Neoplasia Type 2 will be an ideal source of up-to-date information for a wide range of practitioners, including endocrinologists, oncologists, internal medicine specialists, geneticists, and nuclear medicine physicians.
942 _2lcc
_cLE
650 7 _aTiroides
_xCáncer
_0comprobar BNE19901173697
_2embne
_9173915
700 1 _aRaue, Friedhelm
_eeditor literario
_995461
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-22542-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12911264
_b10-10-17
_c10-02-16
988 _aSpringer_Medicine_2015
998 _am
_a_alco
_a_vill
_b14-12-16
_cm
_dz
_ea
_feng
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945 _aRC280.T6 .M438 2015 EB
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