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007			cr nn 008mamaa
008			150619s2015 gw | s |||| 0|eng d
020			_a9783319167336
024	7		_a10.1007/978-3-319-16733-6 _2doi
050		4	_aRC268.48 _b2015 EB
082	0	4	_a614.5999
245	0	0	_aMurine Models, Energy Balance, and Cancer _cedited by Nathan A. Berger
260			_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (XV, 295 p.) _b40 ilustraciones, 36 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aEnergy Balance and Cancer _x2199-2622 _v10
505	0		_aRelevance of Circadian Rhythm in Cancer -- Environmental Manipulation and Neuropeptide Effects on Energy Balance and Cancer -- The MRL Mouse: A Model of Regeneration and Cancer -- Living Large: What Mouse Models Reveal about Growth Hormone and Obesity -- Mouse Models to Study Obesity Effects on Hematologic Malignancies -- Energy Balance, IGF-1 and Cancer:Âáusal Lessons from Genetically Engineered Mice -- Mouse Models to Study Leptin in Breast Cancer Stem Cells -- Mouse Models used to study the effects of Diabetes, Insulin and IGFs on cancer -- Impact of Energy Balance on Chemically Induced Mammary Carcinogenesis in the Rat -- Models and Mechanisms of High Fat Diet Promotion of Pancreatic Cancer -- Maternal energetics and the developmental origins of prostate cancer in offspring -- Mouse Models to Study the Effect of Natural Products on Obesity Associated -- Mouse Models to Study Metformin Effects in Carcinogenesis
520	3		_aThis volume provides a transdisciplinary and translational review of many of the leading murine models used to study the mechanisms, mediators and biomarkers linking energy balance to cancer. It provides a review of murine models that should be of interest to basic, clinical and applied research investigators as well as nutrition scientists and students that work in cancer prevention, cancer control and treatment. The worldwide obesity pandemic has been extensively studied by epidemiologic and observational studies and even, in some cases, by randomized controlled trials. However, the development and control of obesity, its comorbidities and its impact on cancer usually occurs over such long periods that it is difficult, if not impossible to conduct randomized controlled trials in humans to investigate environmental contributions to obesity, energy balance and their impact on cancer. In contrast, model organisms, especially mice and rats, provide valuable assets for performing these studies under rigorously controlled conditions and in sufficient numbers to provide statistically significant results. In this volume, many of the leading and new murine models used to study the mechanisms and mediators linking cancer with obesity, sleep, exercise, their modification by environment and how they may continue to be used to further elucidate these relations as well as to explore preclinical aspects of prevention and/or therapeutic intervention are considered. This volume provides an important compilation and analysis of major experimental systems and principles for further preclinical research with translational impact on energy balance and cancer
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
650		7	_aCáncer _xEtiología _9170296 _0comprobar BNE19901092798 _2embne
700	1		_aBerger, Nathan A _eeditor literario _984721 _0Local
830		0	_aEnergy Balance and Cancer _x2199-2622 _v10 _9133182
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-16733-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319167336
907			_a.b12909993 _b10-10-17 _c10-02-16
988			_aSpringer_Medicine_2015
998			_am _a_alco _a_vill _b11-08-17 _cm _dz _ek _feng _ggw _h0
945			_aRC268.48 .M875 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11577678 _z06-04-17
999			_c82359 _d82359 _x1