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020 _a9783319139579
024 7 _a10.1007/978-3-319-13957-9
_2doi
050 4 _aRC270
_b2015 EB
245 1 0 _aPre-Analytics of Pathological Specimens in Oncology
_cedited by Manfred Dietel, Christian Wittekind, Gianni Bussolati, Moritz von Winterfeld.
260 _aCham, Switzerland
_bSpringer
_c2015
300 _a1 recurso en línea (VI, 133 páginas)
_b65 ilustraciones, 61 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aRecent Results in Cancer Research
_x0080-0015
_v199
505 0 _aWhat Is Pre-Analytics in Surgical Pathology? -- Histologic Validation of Vacuum Sealed Formalin -- Free Tissue Preservation and Transport System -- Pre-Analytics and Molecular Pathology -- Experiences in Vacuum Preparation of Routine Specimens -- Tissue Heterogeneity as a Pre-Analytical Source of Variability -- Vacuum Fixation of Breast Specimens Before Grossing -- How Do Short Fixation and Rapid Microwave Processing Affect Her2 Testing? -- Current Projects in Pre-Analytics â€רere to Go? -- Nucleic Acid Extraction from FFPE Tissue as Critical Preanalytic Step for NGS Applications -- Experiences With Pre-Analytics of Lung Specimen -- Experiences With Pre-Analytics of GI-Specimen -- Bone Marrow Work-Up -- Two-Temperature Fixation Preserves Activation Status with High Efficiency -- Towards the Lean Lab. The Industry Challenge. Â{uE000}
520 3 _aThis book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase â€{u0D28}e period from surgical removal of tissue to the start of pathological processing â€{u0A21}ve remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up.
710 2 _aSpringerLink (Online service)
_0Local
_9106996
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650 7 _aLaboratorios
_2embne
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650 7 _aPatología
_2embne
_9138489
650 2 7 _aPatología
_2embne
_9138489
700 1 _aDietel, Manfred
_eeditor literario
_995096
_0Local
700 1 _aWittekind, Christian
_eeditor literario
_995097
_0Local
700 1 _aBussolati, Gianni
_eeditor literario
_995098
_0Local
700 1 _aWinterfeld, Moritz von
_eeditor literario
_995099
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-13957-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12909178
_b10-10-17
_c10-02-16
988 _aSpringer_Medicine_2015
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