000			03930nam a22004335i 4500
999			_c82207 _d82207
001			82207
003			ES-MaUEC
005			20230214154845.0
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007			cr nn 008mamaa
008			140828s2015 gw | s |||| 0|eng d
020			_a9783319107110
024	7		_a10.1007/978-3-319-10711-0 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_aRS201.N35 _b2015 EB
100	1		_aShah, Rohan. _994976 _0Local
245	1	0	_aLipid Nanoparticles : _bProduction, Characterization and Stability _cby Rohan Shah, Daniel Eldridge, Enzo Palombo, Ian Harding.
260			_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (IX, 97 páginas) _b30 ilustraciones, 18 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aSpringerBriefs in Pharmaceutical Science & Drug Development _x1864-8118
505	0		_aIntroduction -- Composition and structure -- Production techniques -- Characterization -- Physicochemical stability.
520	3		_aWhat are lipid nanoparticles?Âȯw are they structured?Âȯw are they formed? What techniques are best to characterize them?Âȯw great is their potential as drug delivery systems?These questions and more are answered in this comprehensive and highly readable work on lipid nanoparticles. This work sets out to provide the reader with a clear andÂ{u5BA4}erstandableÂ{u5BA4}erstanding of the current practices in formulation, characterization and drug delivery of lipid nanoparticles. AÂ{u3BED}prehensive description ofÂ{u4A25} current understanding of synthesis, characterization, stability optimization and drug incorporation of solid lipid nanoparticles is provided. Nanoparticles have attracted great interest over the past few decades with almost exponential growth in their research and application. Their small particle size and subsequent high surface area make them ideal in many uses, but particularly as drug carrier systems.Â{uE86E}noparticles made from lipids are especially attractive because of their enhanced biocompatibility imparted by the lipid. TheÂ{u7BF2}k provides a detailed description of the types of lipid nanoparticles available (e.g. SLN, NLC, LDC, PLN) and how they range from imperfect crystalline to amorphous in structure.Â{u3D72}rrent thoughts on where drugs are situated (e.g. in the core, or at the interface) and how this can be manipulated are discussed.The many techniques for production, including the authorâ€{u382F}wn variant of microwave heating, are fully discussed.Â{u4963}hniques for measuring arguably the most important characteristics of particle size and polydispersity are discussed, along with techniques to measure crystallinity, shape and drug capacity.Â{u01A9}nally, a full chapter on techniques for measuring stability, both in the absence and presence of drugs, is discussed, along with suggestions on how to optimize that stability. ThisÂ{u7BF2}k appealsÂ{u4BE0}students of colloid science, practitioners of research into drug delivery and academics alike.
988			_aSpringer_Medicine_2015
650		7	_aTecnología farmacéutica _2embne _9161127
650		7	_aBiotecnología _2embne _9140931
650		7	_aLípidos _2embne _9142933
700	1		_aEldridge, Daniel _0Local _994977
700	1		_aPalombo, Enzo. _994978 _0Local
700	1		_aHarding, Ian _0Local _994979
710	2		_aSpringerLink (Online service) _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-10711-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12908472 _b10-10-17 _c10-02-16
942			_2lcc _cLE
945			_aRS201.N35 S534 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11576157 _z06-04-17
998			_dz _e- _feng _ggw _h0