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008			140916s2015 xxu| s |||| 0|eng d
020			_a9781493907274
024	7		_a10.1007/978-1-4939-0727-4 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_aRB155 _b2015 EB
245	1	0	_aGenomic Applications in Pathology _cedited by George Jabboure Netto, Iris Schrijver.
260			_aNew York _bSpringer _c2015
300			_a1 recurso en línea (XV, 622 páginas) _b85 ilustraciones, 79 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aCurrent Massively Parallel Sequencing Technologies: Platforms and Reporting Considerations -- Emerging Next Generation Sequencing Technologies -- Transcriptome Sequencing (RNA-Seq) -- miRNA Expression Assays -- Circulating Tumor Cells: Enrichment and Genomic Applications -- Circulating Cell-free DNA for Molecular Diagnostics and Therapeutic Monitoring -- Genomic Pathology: Training for New Technology -- Implementation of Genomic Sequencing Assays -- Regulatory and Reimbursement Issues in Genomic Testing -- Patents and Proprietary Assays -- Ethical Issues in Clinical Genetics and Genomics -- Transitioning Discoveries from Cancer Genomics Research Laboratories into Pathology Practice -- Bioinformatics Tools in Clinical Genomics -- Next Generation Sequencing for Single Gene Analysis -- Next Generation Sequencing for Gene Panels -- Implementation of Exome Sequencing Assays -- Implementation of Genome Sequencing Assays -- Clinical Information Systems in the Era of Personalized Medicine -- Reporting Clinical Genomic Assay Results and the Role of the Pathologist -- Genomic Applications in Hematologic Oncology -- Genomic Applications in Brain Tumors -- Genomic Applications in Head and Neck Cancers -- Genomic Applications in Breast Carcinoma -- Genomic Applications in Pulmonary Malignancies -- Genomic Applications in Colorectal and Pancreatic Tumors -- Molecular Pathology of Genitourinary Cancers: Translating the Cancer Genome to the Clinic -- Genomic Applications in Gynecologic Malignancies -- Genomic Applications in Epithelial Ovarian Malignancies -- Genomic Applications in Soft Tissue Sarcomas -- Genomic Applications in Inherited Genetic Disorders -- Genomic Applications in Pharmacogenomics -- Sequencing Cell Free DNA in the Maternal Circulation to Screen for Down Syndrome and Other Common Aneuploidies -- Genomic Applications in the Clinical Management of Infectious Diseases. .
520	3		_aGenomic Applications in PathologyÂ{u0CAF}vides a state-of-the art review of the scientific principles underlying next generation genomic technologies and the required bioinformatics approaches to analyses of the daunting amount of data generated by current and emerging genomic technologies. Implementation roadmaps for various clinical assays such as single gene, gene panels, whole exome and whole genome assays are discussed together with issues related to reporting, including the pathologistâ€{u3832}ole in interpretation and clinical integration of genomic tests results. Genomic applications for site-specific solid tumors and hematologic neoplasms are detailed, as well as genomic applications in pharmacogenomics, inherited genetic diseases, and infectious diseases. The latest iteration of practice recommendations and guidelines in genomic testing, put forth by stakeholder professional organizations such as the Association for Molecular PathologyÂ{u086E}d the College of American Pathologists, are also discussed in the volume, as well as regulatory issues and laboratory accreditation related to genomic testing. Written by experts in the field, Genomic Applications in PathologyÂ{u0CAF}vides a comprehensive resource that is of great value to practicing molecular pathologists, hematopathologists, other subspecialized pathologists, general pathologists, pathology trainees, oncologists, and geneticists.
650		7	_aGenética médica _2embne _9144879
650		7	_aPatología molecular _2embne _9158317
700	1		_aNetto, George Jabboure _eeditor literario _994555 _0Local
700	1		_aSchrijver, Iris _eeditor literario _994556 _0Local
710	2		_aSpringerLink (Online service) _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-0727-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12906037 _b10-10-17 _c10-02-16
942			_2lcc _cLE
945			_aRB155 .G466 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11573727 _z06-04-17
988			_aSpringer_Medicine_2015
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gxxu _h0