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001			81962
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007			cr nn 008mamaa
008			150629s2015 xxu| s |||| 0|eng d
020			_a9781489976062
024	7		_a10.1007/978-1-4899-7606-2 _2doi
050		4	_aRC93.O67 _b2015 EB
245	1	0	_aPost-Traumatic Arthritis : _bPathogenesis, Diagnosis and Management _cedited by Steven A. Olson, MD, Farshid Guilak, PhD.
260			_aBoston, MA _bSpringer _c2015
300			_a1 recurso en línea (XX, 360 páginas) _b98 ilustraciones, 65 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aSection I: The Problem of Post-Traumatic Arthritis -- Arthritis that Develops after Joint Injury: Is it Post-Traumatic Arthritis or Post-Traumatic OsteoArthritis? -- Post-Traumatic Arthritis: Definitions and Burden of Disease -- Arthritis after Joint Injury: The Military Experience -- Section II: Experimental Models of Joint Injury -- In Vitro Cartilage Explant Injury Models -- Animal Models of Meniscal Injury in Post-Traumatic Arthritis.-Anterior Cruciate Transection/Disruption Models of Posttraumatic Arthritis -- Closed Joint ACL Disruption Murine Model of PTA -- Whole Joint Models of Articular Injury and Articular Fracture -- Instability: Dynamic Loading Models -- Survey of Animal Models in Post-Traumatic Arthritis: Choosing the Right Model to Answer the Right Question -- Section III: Peri-articular Tissue Response to Joint Injury -- The Response of Cartilage to Injury -- The Response of Subchondral Bone to Injury -- Genetic Variability in the Response to Injury -- Aging and Post-Traumatic Arthritis.-Potential Mechanisms of PTA: Cell Death -- Potential Mechanisms of PTA: Inflammation -- Potential Mechanisms of PTA: Oxidative Stress -- Potential Mechanisms of PTA: Alterations in Joint Loading -- Section IV: Clinical Assessment and Treatment of Patients with Joint Injury -- Imaging Specific to Cartilage Injury -- Outcomes of ACL Injury: The MOON Consortium -- Current Treatment and Outcomes of Intra-articular Fractures -- Non-arthroplasty Treatments for PTA in the Lower Extremity -- Results of Arthroplasty in Post-Traumatic Arthritis -- Section V: Developing and Future Assessment and Therapies -- Measurement of Severity of Injury after Articular Fracture and Correlation with Post-Traumatic Arthritis Development -- Biomarkers of PTA -- Potential Targets for Pharmacologic Therapies for Prevention of PTA.-Â{u3D25}m Cells Therapies for Post-Traumatic Arthritis -- Unanswered Questions and Future Directions.
520	3		_aBringing together the most up-to-date research on post-traumatic arthritis (PTA) and its management, this book is a comprehensive presentation of the current thinking on all aspects of the mechanisms of joint injury and subsequent development of PTA. Divided into thematic sections, it includes discussions of the incidence and burden of PTA, both in society at large and in the military population specifically; the relevant experimental work on PTA, from basic science to animal models; peri-articular tissue responses to of joint injury and potential mechanisms of PTA; the current clinical assessment and treatment of common joint injuries leading to PTA; and emerging technologies and treatments for PTA, including biomarkers and stem cell therapies. Taken together, it will be an invaluable resource for orthopedic surgeons, rheumatologists and other joint injury researchers and clinicians.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
650		7	_aReumatología _0 _2embne _9141883
650		7	_aMedicina deportiva _0 _2embne _9138384
650	2	7	_aReumatología _0 _2embne _9141883
700	1		_aOlson, MD, Steven A _eeditor literario _994552 _0Local
700	1		_aGuilak, PhD, Farshid _eeditor literario _994553 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4899-7606-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12906013 _b10-10-17 _c10-02-16
988			_aSpringer_Medicine_2015
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gxxu _h0
945			_aRC93.O67 P678 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11573703 _z06-04-17
999			_c81962 _d81962 _x1