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008			150512s2015 ne | s |||| 0|eng d
020			_a9789401799270
024	7		_a10.1007/978-94-017-9927-0 _2doi
050		4	_aRB155 _b.C667 2015
245	1	0	_aComputational and Statistical Epigenomics _cedited by Andrew E. Teschendorff.
260			_aDordrecht, Netherlands _bSpringer _c2015
300			_a1 recurso en línea (V, 217 páginas) _b42 ilustraciones, 41 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aTranslational Bioinformatics _x2213-2775 _v7
520	3		_aThis book introduces the reader to modern computational and statistical tools for translational epigenomics research. Over the last decade, epigenomics has emerged as a key area of molecular biology, epidemiology and genome medicine. Epigenomics not only offers us a deeper understanding of fundamental cellular biology, but also provides us with the basis for an improved understanding and management of complex diseases. From novel biomarkers for risk prediction, early detection, diagnosis and prognosis of common diseases, to novel therapeutic strategies, epigenomics is set to play a key role in the personalized medicine of the future. In this book we introduce the reader to some of the most important computational and statistical methods for analyzing epigenomic data, with a special focus on DNA methylation. Topics include normalization, correction for cellular heterogeneity, batch effects, clustering, supervised analysis and integrative methods for systems epigenomics. This book will be of interest to students and researchers in bioinformatics, biostatistics, biologists and clinicians alike. Dr. Andrew E. Teschendorff is Head of the Computational Systems Genomics Lab at the CAS-MPG Partner Institute for Computational Biology, Shanghai, China, as well as an Honorary Research Fellow at the UCL Cancer Institute, University College London, UK.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		7	_aBiología molecular _2embne _9139103
650		0	_9138405 _aEpidemiología
650		7	_aBioinformática _2embne _9160489
700	1		_aTeschendorff, Andrew E _eeditor literario _994324 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-017-9927-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12903218 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gne _h0
945			_aRB155 .C667 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11572838 _z06-04-17
999			_c81731 _d81731 _x1