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007			cr nn 008mamaa
008			150327s2015 ne | s |||| 0|eng d
020			_a9789401797535
024	7		_a10.1007/978-94-017-9753-5 _2doi
050		4	_aQR182.2.I46 _bS564 2015
245	1	0	_aSingle Cell Sequencing and Systems Immunology _cedited by Xiangdong Wang.
260			_aDordrecht, Netherlands _bSpringer _c2015
300			_a1 recurso en línea (XI, 177 páginas) _b89 ilustraciones, 62 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aTranslational Bioinformatics _x2213-2775 _v5
505	0		_aPreface -- Significance of Single Cell Sequencing in Future Medicine -- Uncovering Phenotypes with Supercells: Applications to Single-Cell Sequencing -- Single-Cell Sequencing of Microorganisms -- Application of single-cell sequencing in dynamic transcriptomes -- System Immunology in Metabolic Research of Dendritic Cells -- FOXP3+ Treg Cells and Systems Biology Approaches to Studying Their Function -- γÎT́ Cells and αβT Cells -- Prolymphocyte: Lymphocytes and Bioinformatics -- Lymphocytes in liver cancer -- Early biomarkers of hepatocyte necrosis -- Protocol of Single Cell Isolation by Flow Cytometry -- Single-cell based omics-the new era of human disease and medicine -- Cancer bioinformatics.Â{u2802}Â�Â{u2802}Â{u282E}.
520	3		_aThe volume focuses on the genomics, proteomics, metabolomics, and bioinformatics of a single cell, especially lymphocytes and on understanding the molecular mechanisms of systems immunology. Based on the authorâ€{u3830}ersonal experience, it provides revealing insights into the potential applications, significance, workflow, comparison, future perspectives and challenges of single-cell sequencing for identifying and developing disease-specific biomarkers in order to understand the biological function, activation and dysfunction of single cells and lymphocytes and to explore their functional roles and responses to therapies. It also provides detailed information on individual subgroups of lymphocytes, including cell characters, function, surface markers, receptor function, intracellular signals and pathways, production of inflammatory mediators, nuclear receptors and factors, omics, sequencing, disease-specific biomarkers, bioinformatics, networks and dynamic networks, their role in disease and future prospects. Â{u0132}. Xiangdong Wang is a Professor of Medicine, Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Director of the Biomedical Research Center of Zhongshan Hospital, Deputy Director of Shanghai Respiratory Research Institute, Shanghai, China. Â{uE000}
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		0	_9430647 _aProteómica _0
650		7	_aSistemas biológicos _0 _2embne _9403517
650		7	_aInmunología _0 _2embne _9138330
700	1		_aWang, Xiangdong _eeditor literario _986082 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-017-9753-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12903103 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gne _h0
945			_aQR182.2.I46 S564 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11572723 _z06-04-17
999			_c81720 _d81720 _x1